Pfeffer disputerer for ph.d.-graden i helsevitenskap og vil offentlig forsvare avhandlingen:
"Analysis of phase II metabolites of endogenous steroids for enhanced testosterone doping detection."
Avhandlingen er tilgjengelig her! / The doctoral thesis is available here!
Disputasen strømmes og et opptak vil være tilgjengelig i et døgn.
The defense will be streamed, and a recording of the disputation will be available for 24 hours.
Prøveforelesning over oppgitt emne starter kl. 10.15 / The trial lecture starts at 10.15
Tittel/Title: "Dried Blood Spots in Sports Drug Testing: Current Applications, Challenges, and Future Perspectives"
Prøveforelesningen strømmes her / The trial lecture will be streamed here.
Disputasen starter kl. 12.15 / The defense starts at 12.15
Disputasen strømmes her / The defense will be streamed here
Populærvitenskapelig sammendrag av avhandlingen/ Summary of the thesis:
Novel biomarkers enable better detection of testosterone doping - by focusing on previously overlooked metabolites, testosterone doping can now be detected for much longer than with current techniques.
Currently, athletes can cheat using testosterone and escape detection unless tested within a few days. Worse, certain methods, like low-dose gels, are almost undetectable.
We investigated the applicability of “phase II metabolites” to improve detection. In a clinical study with male and female participants, urine samples were collected after administering testosterone as tablets and gels. This allowed us to observe formulation- and sex-specific results. Using liquid chromatography – mass spectrometry, we identified novel biomarkers that extend the detection window for testosterone misuse to up to 4 weeks.
These biomarkers will soon be implemented in international sports testing, revolutionizing anti-doping measures and ensuring fair play in sports.
Veiledere/ Supervisors:
Hovedveileder/Main supervisor:
Professor Guro Forsdahl, Department of Pharmacy, Faculty of Health Sciences, UiT – The Arctic University of Norway
Biveileder/supervisor:
Professor Günter Gmeiner, Doping Control Laboratory, Seibersdorf Laboratories, Austria
Bedømmelseskomité/Defensecomitee:
Ph.d. Thomas Piper, German Sport University Cologne, Cologne, Germany – 1. opponent.
Professor Trine Grønhaug Halvorsen, Department of Pharmacy, University of Oslo – 2. opponent.
Professor emerita Thrina Loennechen, Department of Pharmacy, Faculty of Health Sciences, UiT – The Arctic University of Norway – leder av komité.
Disputasleder/ Leader of defense:
Professor Natasa Skalko-Basnet, Department of Pharmacy, Faculty of Health Sciences, UiT – The Arctic University of Norway
When: 18.12.25 kl 10.15–16.00
Where:
Auditorium Tabletten, Farmasibygget
Location / Campus: Digitalt, Tromsø
Target group: Ansatte, Studenter, Besøkende, Inviterte, Enhet
Contact: Andrea Jennerwein
E-boastta: andrea.jennerwein@uit.no