Bilde av Johnsen, Pål Jarle
Bilde av Johnsen, Pål Jarle
Farmasiija instituhtta paal.johnsen@uit.no +4777623156 +47 47688974 Tromsø FARM F4. 218

Johnsen, Pål Jarle



  • Christopher Frøhlich, Vidar Sørum, Nobuhiko Tokuriki, Pål Jarle Johnsen, Ørjan Samuelsen :
    Evolution of β-lactamase-mediated cefiderocol resistance
    Journal of Antimicrobial Chemotherapy 2022 ARKIV / DOI
  • Vidar Sørum, Emma Lu Øynes, Anna Sollied Møller, Klaus Harms, Ørjan Samuelsen, Nicole L. Podnecky et al.:
    Evolutionary Instability of Collateral Susceptibility Networks in Ciprofloxacin-Resistant Clinical Escherichia coli Strains
    mBio 2022 ARKIV / DOI
  • Macaulay Winter, Angus Buckling, Klaus Harms, Pål Jarle Johnsen, Michiel Vos :
    Antimicrobial resistance acquisition via natural transformation: context is everything
    Current Opinion in Microbiology 2021 ARKIV / DOI
  • Jonina Gudmundsdottir, Elizabeth G. Aarag Fredheim, Catharina I.M. Koumans, Joachim Hegstad, Po-Cheng Tang, Dan I. Andersson et al.:
    The chemotherapeutic drug methotrexate selects for antibiotic resistance
    EBioMedicine 2021 ARKIV / DOI
  • Rebecca Ashley Gladstone, Alan McNally, Anna Kaarina Pöntinen, Gerry Tonkin-Hill, John A. Lees, Kusti Onni Skytén et al.:
    Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002–17: a nationwide, longitudinal, microbial population genomic study
    Lancet Microbe 29. Jun 2021 FULLTEKST / ARKIV / DOI
  • Pål Jarle Johnsen, João Alves Gama, Klaus Harms :
    Bacterial evolution on demand
    eLIFE 2021 ARKIV / DOI
  • Julia Kloos, João A Gama, Joachim Hegstad, Ørjan Samuelsen, Pål J Johnsen :
    Piggybacking on Niche Adaptation Improves the Maintenance of Multidrug-Resistance Plasmids
    Molecular Biology and Evolution (MBE) 2021 ARKIV / DOI
  • Sergio Arredondo Alonso, Anna Kaarina Pöntinen, Francois Pierre Alexandre Cleon, Rebecca Ashley Gladstone, Anita C. Schürch, Pål Jarle Johnsen et al.:
    A high-throughput multiplexing and selection strategy to complete bacterial genomes
    GigaScience 2021 ARKIV / DOI
  • Christopher Frøhlich, João Alves Gama, Klaus Harms, Viivi H. A. Hirvonen, Bjarte Aarmo Lund, Marc W. van der Kamp et al.:
    Cryptic β-Lactamase Evolution Is Driven by Low β-Lactam Concentrations
    mSphere 2021 ARKIV / DOI
  • Joao Pedro Alves Gama, Julia Maria Kloos, Pål Jarle Johnsen, Ørjan Samuelsen :
    Host dependent maintenance of a blaNDM-1-encoding plasmid in clinical Escherichia coli isolates
    Scientific Reports 2020 ARKIV / DOI
  • Julia Maria Kloos, Joao Pedro Alves Gama, Pål Jarle Johnsen, Ørjan Samuelsen :
    Host dependent maintenance of a blaNDM-1-encoding plasmid in clinical Escherichia coli isolates
    Scientific Reports 2020 DOI
  • Julia Maria Kloos, Pål Jarle Johnsen, Klaus Harms :
    Tn1 transposition in the course of natural transformation enables horizontal antibiotic resistance spread in Acinetobacter baylyi
    Microbiology (Reading) 2020 ARKIV / DOI
  • Christopher Frøhlich, Vidar Sørum, Ane Molden Thomassen, Pål Jarle Johnsen, Hanna-Kirsti S. Leiros, Ørjan Samuelsen :
    OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs
    mSphere 2019 ARKIV / DOI
  • Nicole L. Podnecky, Elizabeth Aarag, Julia Maria Kloos, Vidar Sørum, Raul Primicerio, Adam Paul Roberts et al.:
    Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli.
    Nature Communications 10. Sep 2018 ARKIV / DOI
  • Nils Fredrik Hülter, Vidar Sørum, Kristina Borch-Pedersen, Mikkel Meyn Liljegren, Ane Utnes, Raul Primicerio et al.:
    Costs and benefits of natural transformation in Acinetobacter baylyi
    BMC Microbiology 2017 ARKIV / DOI
  • Maria Chiara Di Luca, Vidar Sørum, Irina Starikova, Julia Maria Kloos, Nils Fredrik Hülter, Mohammed Umaer Naseer et al.:
    Low biological cost of carbapenemase-encoding plasmids following transfer from Klebsiella pneumoniae to Escherichia coli
    Journal of Antimicrobial Chemotherapy 2016 DOI
  • Klaus Harms, Asbjørn Lunnan, Nils Hulter, Tobias Mourier, Lasse Vinner, Cheryl P Andam et al.:
    Substitutions of short heterologous DNA segments of intragenomic or extragenomic origins produce clustered genomic polymorphisms
    Proceedings of the National Academy of Sciences of the United States of America 2016 ARKIV / DOI
  • Jan Engelstädter, Klaus Harms, Pål Jarle Johnsen :
    The evolutionary dynamics of integrons in changing environments
    The ISME Journal 2016 DOI
  • Amy Mcleman, Pawel Sierocinski, E Hesse, A Buckling, G Perron, Nils Fredrik Hülter et al.:
    No effect of natural transformation on the evolution of resistance to bacteriophages in the Acinetobacter baylyi model system.
    Scientific Reports 21. Nov 2016 ARKIV / DOI
  • Ole Herman Ambur, Jan Engelstädter, Pål Jarle Johnsen, Eric L. Miller, Daniel E. Rozen :
    Steady at the wheel: Conservative sex and the benefits of bacterial transformation
    Philosophical Transactions of the Royal Society of London. Biological Sciences 2016 ARKIV / DOI
  • Luigimaria Borruso, Klaus Harms, Pål Jarle Johnsen, Kaare Magne Nielsen, Lorenzo Brusetti :
    Distribution of class 1 integrons in a highly impacted catchment
    Science of the Total Environment 2016 FULLTEKST / DOI
  • Ane Live Gunnes Utnes, Vidar Sørum, Nils Fredrik Hülter, Raul Primicerio, Joachim Hegstad, Julia Maria Kloos et al.:
    Growth phase-specific evolutionary benefits of natural transformation in Acinetobacter baylyi
    The ISME Journal 2015 DOI
  • Iren Høyland Löhr, Nils Fredrik Hülter, Eva Bernhoff, Pål Jarle Johnsen, Arnfinn Sundsfjord, Mohammed Umaer Naseer :
    Persistence of a pKPN3-like CTX-M-15-encoding IncFIIK plasmid in a Klebsiella pneumonia ST17 host during two years of intestinal colonization
    PLOS ONE 2015 ARKIV / FULLTEKST / DOI
  • Bruce R: Levin, Fernando Baquero, Pål Jarle Johnsen :
    A model-guided analysis and perspective on the evolution and epidemiology of antibiotic resistance and its future
    Current Opinion in Microbiology 2014 DOI
  • Shweta Fulsundar, Klaus Harms, Gøril Eide Flaten, Pål Jarle Johnsen, Balu Ananda Chopade, Kaare Magne Nielsen :
    Gene transfer potential of outer membrane vesicles of Acinetobacter baylyi and effects of stress on vesiculation
    Applied and Environmental Microbiology 2014 ARKIV / DOI
  • Søren Overballe-Petersen, Klaus Harms, Ludovic A.A. Orlando, J. Victor Moreno Mayar, Simon Rasmussen, Tais W. Dahl et al.:
    Bacterial natural transformation by highly fragmented and damaged DNA
    Proceedings of the National Academy of Sciences of the United States of America 2013 DOI
  • Irina Starikova, Mohammed Al-Haroni, Guido Werner, Adam P. Roberts, Vidar Sørum, Kåre M. Nielsen et al.:
    Fitness costs of various mobile genetic elements in Enterococcus faecium and Enterococcus faecalis
    Journal of Antimicrobial Chemotherapy 2013 ARKIV / DOI
  • Sara Domingues, Klaus Harms, W. Florian Fricke, Pål Jarle Johnsen, Gabriela J. da Silva, Kåre M. Nielsen :
    Natural Transformation Facilitates Transfer of Transposons, Integrons and Gene Cassettes between Bacterial Species
    PLoS Pathogens 2012 FULLTEKST / ARKIV / DOI
  • Irina Starikova, Klaus Harms, Pål Haugen, Tracy Munthali Lunde, Raul Primicerio, Ørjan Samuelsen et al.:
    A Trade-off between the Fitness Cost of Functional Integrases and Long-trem stability of Integrons
    PLoS Pathogens 2012 FULLTEKST / ARKIV / DOI
  • Kåre M. Nielsen, Jessica Louise Ray, Pål Jarle Johnsen :
    Horizontal gene transfer: the uptake of extracellular DNA in bacteria
    Elsevier 2012
  • Julia Hurler, Ole Alexander Berg, Merete L. Skar, Anne Hilde Conradi, Pål Jarle Johnsen, Natasa Skalko-Basnet :
    Improved burns therapy: Liposomes-in-hydrogel delivery system for mupirocin
    Journal of Pharmaceutical Sciences 2012 DOI
  • Julia Maria Kloos, Lea Jänisch, Anna Kaarina Pöntinen, Ørjan Samuelsen, Pål Jarle Johnsen, Jukka Corander et al.:
    Different metabolic proficiency among dominant ExPEC lineages
    2022
  • Christopher Frøhlich, Adrian H. Bunzel, Marc W. Van Der Kamp, Adrian J. Mulholland, Hanna-Kirsti Schrøder Leiros, Pål Jarle Johnsen et al.:
    Positive epistasis drives the molecular evolution of the carbapenemase OXA-48
    2022
  • João Alves Gama, Julia Maria Kloos, Joachim Hegstad, Ørjan Samuelsen, Pål Jarle Johnsen :
    Plasmid cost alleviation as a consequence of niche-adaptation
    2021
  • Julia Maria Kloos, João Alves Gama, Joachim Hegstad, Ørjan Samuelsen, Pål Jarle Johnsen :
    Plasmid Cost Alleviation By Hitchhiking On Niche-adaptation
    2021
  • Julia Maria Kloos, Joao Pedro Alves Gama, Joachim Hegstad, Ørjan Samuelsen, Pål Jarle Johnsen :
    E. coli Niche Adaptation Improves Plasmid Maintenance
    2021
  • Sybil Akua Okyerewa Obuobi, Kjersti Julin, Elizabeth G. Aarag Fredheim, Pål Jarle Johnsen, Mona Johannessen, Natasa Skalko-Basnet :
    Liposomal delivery of antibiotic loaded DNA nanogels against intracellular infections
    2020
  • Vidar Sørum, Anna Sollied Møller, Pål Jarle Johnsen, Ørjan Samuelsen, Sören Abel, Nicole L. Podnecky :
    Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains
    2019
  • Vidar Sørum, Anna Sollied Møller, Sören Abel, Ørjan Samuelsen, Nicole L. Podnecky, Pål Jarle Johnsen :
    Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains
    2019
  • Vidar Sørum, Emma Lu Øynes, Anna Møller, Nicole L. Podnecky, Sören Abel, Ørjan Samuelsen et al.:
    Evolutionary stability of collateral susceptibility networks in clinical Escherichia coli strains
    2019
  • Elizabeth G. Aarag Fredheim, Nicole Podnecky, Angie Carola Alarcon Rios, Jessica Nguyen Tran, Chantal Verstappen, Klaus Harms et al.:
    Gentamicin collateral sensitivity of ciprofloxacin resistant Escherichia coli is opposed by the rapid development of gentamicin resistance
    2019
  • Christopher Frøhlich, Hanna-Kirsti S. Leiros, Pål Jarle Johnsen, Ørjan Samuelsen :
    Sub-inhibitory concentrations of ceftazidime drive evolution of the OXA-48 carbapenemase
    2019
  • Christopher Frøhlich, Pål Jarle Johnsen, Hanna-Kirsti Schrøder Leiros, Ørjan Samuelsen :
    Evolution of OXA-48 under sub-MIC conditions
    2019
  • Christopher Frøhlich, Vidar Sørum, Hanna-Kirsti S. Leiros, Pål Jarle Johnsen, Ørjan Samuelsen :
    Development of OXA-48 mediated ceftazidme-avibactam resistance is associated with an evolutionary trade-off
    2018
  • Julia Maria Kloos, Joao Pedro Alves Gama, Ørjan Samuelsen, Pål Jarle Johnsen :
    Klebsiella pneumoniae MDR-encoding plasmids in clinical isolates of uropathogenic Escherichia coli: plasmid-host co-evolution and its effect on fitness cost of plasmid-mediated resistance
    2018
  • Julia Maria Kloos, Joao Pedro Alves Gama, Ørjan Samuelsen, Pål Jarle Johnsen :
    Plasmid-host co-evolution of Klebsiella pneumoniae MDR-encoding plasmids in clinical isolates of uropathogenic Escherichia coli: effect on fitness cost of plasmid-mediated resistance
    2018
  • Julia Maria Kloos, Kaare Magne Nielsen, Pål Jarle Johnsen, Klaus Harms :
    Natural transformation of Acinetobacter baylyi by transposons
    2017
  • Julia Maria Kloos, Kaare Magne Nielsen, Pål Jarle Johnsen, Klaus Harms :
    Transposition during natural transformation facilitates spread of antibiotic resistance determinants in Acinetobacter baylyi
    2016
  • Klaus Harms, Irina Starikova, Pål Jarle Johnsen :
    Costly Class-1 integrons and the domestication of the the functional integrase
    Mobile Genetic Elements 2013 DOI
  • Pål Jarle Johnsen :
    Is it more to bacterial sex than exploring the fitness landscape of other organisms?
    2012

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