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Samuelsen, Ørjan

Professor Farmasiija instituhtta
Norsk flaggikon Engelsk flaggikon

  • Hegstad, Kristin; Samuelsen, Ørjan; Hegstad, Joachim; Sundsfjord, Arnfinn. Molecular methods for detection of antibacterial resistance genes: rationale and applications. Wolters Kluwer 2015 ISBN 978-1-4511-7675-9.s 408 - 449.
  • Karah, Nabil; Haldorsen, Bjørg; Hegstad, Kristin; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Species identification and molecular characterization of Acinetobacter spp. blood culture isolates from Norway. Journal of Antimicrobial Chemotherapy 2011; Volum 66 (4). ISSN 0305-7453.s 738 - 744.s doi: 10.1093/jac/dkq521.
  • Frøhlich, Christopher; Gama, João Alves; Harms, Klaus; Hirvonen, Viivi H. A.; Lund, Bjarte Aarmo; van der Kamp, Marc W.; Johnsen, Pål Jarle; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Cryptic β-Lactamase Evolution Is Driven by Low β-Lactam Concentrations. mSphere 2021. ISSN 2379-5042.s doi: 10.1128/mSphere.00108-21.

  • Samuelsen, Ørjan; Åstrand, Ove Alexander Høgmoen; Frøhlich, Christopher; Heikal, Adam; Skagseth, Susann; Carlsen, Trine Josefine Olsen; Leiros, Hanna-Kirsti S.; Bayer, Annette; Schnaars, Christian; Kildahl-Andersen, Geir; Lauksund, Silje; Finke, Sarah; Huber, Sandra; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Økstad, Ole Andreas; Rongved, Pål. ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo. (https://aac.asm.org/content/early/2020/03/11/AAC.02415-19.long) Antimicrobial Agents and Chemotherapy 2020; Volum 64 (6). ISSN 0066-4804.s doi: 10.1128/AAC.02415-19.

  • Frøhlich, Christopher; Sørum, Vidar; Huber, Sandra; Samuelsen, Ørjan; Berglund, Fanny; Kristiansson, Erik; Kotsakis, Stathis D.; Marathe, Nachiket; Larsson, DG Joakim; Leiros, Hanna-Kirsti Schrøder. Structural and biochemical characterization of the environmental MBLs MYO-1, ECV-1 and SHD-1. Journal of Antimicrobial Chemotherapy 2020; Volum 75. ISSN 0305-7453.s 2554 - 2563.s doi: 10.1093/jac/dkaa175.

  • Ludden, Catherine; Lötsch, Felix; Alm, Erik; Kumar, Narender; Johansson, Karin; Albiger, Barbara; Huang, Te-Din; Denis, Olivier; Hammerum, Anette M.; Hasman, Henrik; Jalava, Jari; Räisänen, Kati; Dortet, Laurent; Jousset, Agnès B.; Gatermann, Sören; Haller, Sebastian; Cormican, Martin; Brennan, Wendy; Grosso, Maria Del; Monaco, Monica; Schouls, Leo; Samuelsen, Ørjan; Pirš, Mateja; Cerar, Tjaša; Oteo-Iglesias, Jésus; Pérez-Vázquez, Maria; Sjöström, Karin; Edquist, Petra; Hopkins, Katie L.; Struelens, Marc J.; Palm, Daniel; Monnet, Dominique L.; Kohlenberg, Anke. Cross-border spread of blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae: a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019. Eurosurveillance 2020; Volum 25 (20). ISSN 1025-496X.s doi: 10.2807/1560-7917.ES.2020.25.20.2000627.

  • Pedersen, Torunn Annie; Tellevik, Marit Gjerde; Kommedal, Øyvind; Lindemann, Paul Christoffer; Moyo, Sabrina John; James Peter, Jessin Janice; Blomberg, Bjørn; Samuelsen, Ørjan; Langeland, Nina. Horizontal plasmid transfer among klebsiella pneumoniae isolates is the key factor for dissemination of extended-spectrum β-lactamases among children in Tanzania. mSphere 2020; Volum 5:e00428-20 (4). ISSN 2379-5042.s 1 - 13.s doi: 10.1128/mSphere.00428-20.

  • Leiros, Hanna-Kirsti S.; Thomassen, Ane Molden; Samuelsen, Ørjan; Flach, Carl-Fredrik; Kotsakis, Stathis D.; Larsson, Joakim. Structural insights into the enhanced carbapenemase efficiency of OXA-655 compared to OXA-10. (Fulltekst: https://febs.onlinelibrary.wiley.com/doi/full/10.1002/2211-5463.12935 FEBS Open Bio 2020; Volum 10 (9). ISSN 2211-5463.s 1821 - 1832.s doi: 10.1002/2211-5463.12935.

  • Alves Gama, Joao Pedro; Kloos, Julia Maria; Johnsen, Pål Jarle; Samuelsen, Ørjan. Host dependent maintenance of a blaNDM-1-encoding plasmid in clinical Escherichia coli isolates. Scientific Reports 2020; Volum 10:9332. ISSN 2045-2322.s 1 - 7.s doi: 10.1038/s41598-020-66239-8.

  • Kildahl-Andersen, Geir; Schnaars, Christian; Prandina, Anthony; Radix, Sylvie; Le Borgne, Marc; Jordheim, Lars Petter; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Lauksund, Silje; Fröhlich, Christopher; Samuelsen, Ørjan; Rongved, Pål; Åstrand, Ove Alexander Høgmoen. Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors. MedChemComm 2019; Volum 10 (4). ISSN 2040-2503.s 528 - 537.s doi: 10.1039/c8md00578h.

  • Zykov, Ilya Nikolaevich; Frimodt-Møller, Niels; Småbrekke, Lars; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Efficacy of mecillinam against clinical multidrug-resistant Escherichia coli in a murine urinary tract infection model. International Journal of Antimicrobial Agents 2019; Volum 55 (2). ISSN 0924-8579.s doi: 10.1016/j.ijantimicag.2019.11.008.

  • Elstrøm, Petter; Astrup, Elisabeth; Hegstad, Kristin; Samuelsen, Ørjan; Enger, Hege; Kacelnik, Oliver. The fight to keep resistance at bay, epidemiology of carbapenemase producing organisms (CPOs), vancomycin resistant enterococci (VRE) and methicillin resistant Staphylococcus aureus (MRSA) in Norway, 2006-2017. PLOS ONE 2019; Volum 14:e0211741 (2). ISSN 1932-6203.s 1 - 17.s doi: 10.1371/journal.pone.0211741.

  • Frøhlich, Christopher; Sørum, Vidar; Thomassen, Ane Molden; Johnsen, Pål Jarle; Leiros, Hanna-Kirsti S.; Samuelsen, Ørjan. OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs. mSphere 2019; Volum 4 (2). ISSN 2379-5042.s doi: 10.1128/mSphere.00024-19.

  • Prandina, Anthony; Radix, Sylvie; Le Borgne, Marc; Jordheim, Lars Petter; Bousfiha, Zineb; Fröhlich, Christopher; Leiros, Hanna-Kirsti S.; Samuelsen, Ørjan; Frøvold, Espen; Rongved, Pål; Åstrand, Ove Alexander Høgmoen. Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors. Tetrahedron 2019; Volum 75 (11). ISSN 0040-4020.s 1525 - 1540.s doi: 10.1016/j.tet.2019.02.004.

  • Samuelsen, Ørjan; Hansen, Frank; Aasnæs, Bettina; Hasman, Henrik; Lund, Bjarte Aarmo; Leiros, Hanna-Kirsti S.; Lilje, Berit; James Peter, Jessin Janice; Jakobsen, Lotte; Littauer, Pia; Søes, Lillian M; Holzknecht, Barbara J.; Andersen, Leif P; Stegger, Marc; Andersen, Paal S.; Hammerum, Anette M.. Dissemination and Characteristics of a Novel Plasmid-Encoded Carbapenem-Hydrolyzing Class D β-Lactamase, OXA-436, Found in Isolates from Four Patients at Six Different Hospitals in Denmark. Antimicrobial Agents and Chemotherapy 2018; Volum 62 (1). ISSN 0066-4804.s doi: 10.1128/AAC.01260-17.

  • Taiaroa, George; Samuelsen, Ørjan; Kristensen, Tom; Økstad, Ole Andreas; Heikal, Adam. Complete Genome Sequence of Pseudomonas aeruginosa K34-7, a Carbapenem-Resistant Isolate of the High-Risk Sequence Type 233. Microbiology Resource Announcements (MRA) 2018; Volum 7 (4). ISSN 2169-8287.s 1 - 2.s doi: 10.1128/MRA.00886-18.

  • Roer, Louise; Overballe-Petersen, Søren; Hansen, Frank; Schønning, Kristian; Wang, Mikala; Røder, Bent L; Hansen,, Dennis S; Justesen, Ulrik S; Andersen, Leif P; Fulgsang-Damgaard, David; Hopkins, Katie L; Woodford, Neil; Falgenhauer, Linda; Chakraborty, Trinad; Samuelsen, Ørjan; Sjöström, Karin; Johannesen, Thor B; Ng, Kim; Nielsen, Jens; Ethelberg, Steen; Stegger, Marc; Hammerum, Anette M.; Hasman, Henrik. Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones. mSphere 2018; Volum 3 (4). ISSN 2379-5042.s doi: 10.1128/mSphere.00337-18.

  • Schnaars, Christian; kildahl-Andersen, Geir; Prandina, Anthony; Popal, Roya; Radix, Sylvie; Le Borgne, Marc; Gjøen, Tor; Andresen, Adriana Magalhaes Santos; Heikal, Adam; Økstad, Ole Andreas Løchen; Fröhlich, Christopher; Samuelsen, Ørjan; Lauksund, Silje; Jordheim, Lars Petter; Rongved, Pål; Åstrand, Ove Alexander Høgmoen. Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors. ACS Infectious Diseases 2018; Volum 4 (9). ISSN 2373-8227.s 1407 - 1422.s doi: 10.1021/acsinfecdis.8b00137.

  • Podnecky, Nicole L.; Aarag, Elizabeth; Kloos, Julia Maria; Sørum, Vidar; Primicerio, Raul; Roberts, Adam Paul; Rozen, Daniel E.; Samuelsen, Ørjan; Johnsen, Pål Jarle. Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli.. Nature Communications 2018; Volum 9:3673. ISSN 2041-1723.s 1 - 11.s doi: 10.1038/s41467-018-06143-y.

  • Haldorsen, Bjørg; Giske, Christian G; Hansen, Dennis S; Helgason, Kristjan Orri; Kahlmeter, Gunnar; Löhr, Iren Høyland; Matuschek, Erika; Österblad, Monica; Rantakokko-Jalava, Kaisu; Wang, Mikala; Småbrekke, Lars; Samuelsen, Ørjan; Sundsfjord, Arnfinn. Performance of the EUCAST disc diffusion method and two MIC methods in detection of Enterobacteriaceae with reduced susceptibility to meropenem: the NordicAST CPE study.. Journal of Antimicrobial Chemotherapy 2018; Volum 73 (10). ISSN 0305-7453.s 2738 - 2747.s doi: 10.1093/jac/dky276.

  • Pedersen, Torunn Annie; Sekyere, John Osei; Govinden, Usha; Moodley, Krishnee; Sivertsen, Audun; Samuelsen, Ørjan; Essack, Sabiha Yusuk; Sundsfjord, Arnfinn. Spread of plasmid-encoded NDM-1 and GES-5 carbapenemases among extensively drug-resistant and pandrug-resistant clinical enterobacteriaceae in durban, South Africa. Antimicrobial Agents and Chemotherapy 2018; Volum 62 (5). ISSN 0066-4804.s doi: 10.1128/AAC.02178-17.

  • Zykov, Ilya Nikolaevich; Samuelsen, Ørjan; Jakobsen, Lotte; Småbrekke, Lars; Andersson, Dan I.; Sundsfjord, Arnfinn; Frimodt-Møller, Niels. Pharmacokinetics and pharmacodynamics of fosfomycin and its activity against extended-spectrum-lactamase-, plasmid-mediated AmpC-, and carbapenemase-producing escherichia coli in a murine urinary tract infection model. Antimicrobial Agents and Chemotherapy 2018; Volum 62 (6). ISSN 0066-4804.s doi: 10.1128/AAC.02560-17.

  • Rapp, Ellionor; Samuelsen, Ørjan; Sundqvist, Martin. Detection of carbapenemases with a newly developed commercial assay using Matrix Assisted Laser Desorption Ionization-Time of Flight. Journal of Microbiological Methods 2018; Volum 146. ISSN 0167-7012.s 37 - 39.s doi: 10.1016/j.mimet.2018.01.008.

  • Berg, Einar Sverre; Wester, Astrid Lousie; Ahrenfeldt, J; Mo, Solveig Sølverød; Slettemeås, Jannice Schau; Steinbakk, Martin; Samuelsen, Ørjan; Grude, Nils; Simonsen, Gunnar Skov; Löhr, Iren Høyland; Jørgensen, Silje; Tofteland, Ståle; Lund, O.; Dahle, Ulf R; Sunde, Marianne. Norwegian patients and retail chicken meat share cephalosporin-resistant Escherichia coli and IncK/blaCMY-2 resistance plasmids. Clinical Microbiology and Infection (CMI) 2017; Volum 23 (6). ISSN 1198-743X.s 407.e9 - 407.e15.s doi: 10.1016/j.cmi.2016.12.035.

  • Samuelsen, Ørjan; Overballe-Petersen, Søren; Bjørnholt, Jørgen; Brisse, Sylvain; Doumith, Michel; Woodford, Neil; Hopkins, Katie L.; Aasnæs, Bettina; Haldorsen, Bjørg; Sundsfjord, Arnfinn. Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014. (Fulltekst: http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0187832&type=printable PLOS ONE 2017; Volum 12 (11). ISSN 1932-6203.s doi: 10.1371/journal.pone.0187832.

  • Knudsen, Per Kristian; Brandtzæg, Petter; Høiby, Ernst Arne; Bohlin, Jon; Samuelsen, Ørjan; Steinbakk, Martin; Abrahamsen, Tore G; Müller, Fredrik; Gammelsrud, Karianne Wiger. Impact of extensive antibiotic treatment on faecal carriage of antibiotic-resistant enterobacteria in children in a low resistance prevalence setting. (Fulltekst: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675440/pdf/pone.0187618.pdf PLOS ONE 2017; Volum 12 (11). ISSN 1932-6203.s doi: 10.1371/journal.pone.0187618.

  • Skagseth, Susann; Christopeit, Tony; Akhter, Sundus; Bayer, Annette; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Structural insights into TMB-1 and the role of residues 119 and 228 in substrate and inhibitor binding. Antimicrobial Agents and Chemotherapy 2017; Volum 61:e02602-16 (8). ISSN 0066-4804.s 1 - 19.s doi: 10.1128/AAC.02602-16.

  • Charnock, Colin; Samuelsen, Ørjan; Nordlie, Anne-Lise; Hjeltnes, Bjarne. Use of a Commercially Available Microarray to Characterize Antibiotic-Resistant Clinical Isolates of Klebsiella pneumoniae. Current Microbiology 2017. ISSN 0343-8651.s 1 - 10.s doi: 10.1007/s00284-017-1361-4.

  • Ellington, Matthew J.; Ekelund, Oskar; Aarestrup, Frank Møller; Cantón, Rafael; Doumith, Michel; Giske, Christian G.; Grundman, Hajo; Hasman, Henrik; Holden, Matthew T.G.; Hopkins, Katie L.; Iredell, Jonathan R.; Kahlmeter, Gunnar; Köser, Claudio U.; MacGowan, Alasdair Peter; Mevius, Dik; Mulvey, Michael Richard; Naas, Thierry P.; Peto, Tim E.; Rolain, Jean-Marc; Samuelsen, Ørjan; Woodford, Neil. The role of whole genome sequencing in antimicrobial susceptibility testing of bacteria: report from the EUCAST Subcommittee. Clinical Microbiology and Infection (CMI) 2017; Volum 23 (1). ISSN 1198-743X.s 2 - 22.s doi: 10.1016/j.cmi.2016.11.012.

  • Skagseth, Susann; Akhter, Sundus; Paulsen, Marianne H.; Zeeshan, Muhammad; Lauksund, Silje; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.; Bayer, Annette. Metallo-β-lactamase inhibitors by bioisosteric replacement: preparation, activity and binding. European Journal of Medicinal Chemistry 2017; Volum 135. ISSN 0223-5234.s 159 - 173.s doi: 10.1016/j.ejmech.2017.04.035.

  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Bjerga, Gro Elin Kjæreng; Spencer, James; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Role of residues W228 and Y233 in the structure and activity of metallo-β-lactamase GIM-1. Antimicrobial Agents and Chemotherapy 2016; Volum 60 (2). ISSN 0066-4804.s 990 - 1002.s doi: 10.1128/AAC.02017-15.

  • Di Luca, Maria Chiara; Sørum, Vidar; Starikova, Irina; Kloos, Julia Maria; Hülter, Nils Fredrik; Naseer, Mohammed Umaer; Johnsen, Pål Jarle; Samuelsen, Ørjan. Low biological cost of carbapenemase-encoding plasmids following transfer from Klebsiella pneumoniae to Escherichia coli. Journal of Antimicrobial Chemotherapy 2016; Volum 72 (1). ISSN 0305-7453.s 85 - 89.s doi: 10.1093/jac/dkw350.

  • Zykov, Ilya Nikolaevich; Sundsfjord, Arnfinn; Småbrekke, Lars; Samuelsen, Ørjan. The antimicrobial activity of mecillinam, nitrofurantoin, temocillin and fosfomycin and comparative analysis of resistance patterns in a nationwide collection of ESBL-producing Escherichia coli in Norway 2010–2011. Infectious Diseases 2015; Volum 48 (2). ISSN 2374-4235.s 99 - 107.s doi: 10.3109/23744235.2015.1087648.

  • Karah, Nabil; Samuelsen, Ørjan; Zarrilli, Raffaele; Sahl, Jason W.; Wai, Sun Nyunt; Uhlin, Bernt Eric. CRISPR-cas subtype I-Fb in acinetobacter baumannii: Evolution and utilization for strain subtyping. PLOS ONE 2015; Volum 10 (2). ISSN 1932-6203.s doi: 10.1371/journal.pone.0118205.

  • Leiros, Hanna-Kirsti S.; Edvardsen, Kine Susann Waade; Bjerga, Gro Elin Kjæreng; Samuelsen, Ørjan. Structural and biochemical characterization of VIM-26 shows that Leu224 has implications for the substrate specificity of VIM metallo-β-lactamases. The FEBS Journal 2015; Volum 282 (6). ISSN 1742-464X.s 1031 - 1042.s doi: 10.1111/febs.13200.

  • Moyo, Sabrina John; Haldorsen, Bjørg; Aboud, Said; Blomberg, Bjørn; Maselle, Samuel Y; Sundsfjord, Arnfinn; Langeland, Nina; Samuelsen, Ørjan. Identification of VIM-2-producing Pseudomonas aeruginosa from Tanzania is associated with sequence types 244 and 640 and the location of blaVIM-2 in a TniC integron. Antimicrobial Agents and Chemotherapy 2014; Volum 59 (1). ISSN 0066-4804.s 682 - 685.s doi: 10.1128/AAC.01436-13.

  • Haldorsen, Bjørg; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Increased prevalence of aminoglycoside resistance in clinical isolates of Escherichia coli and Klebsiella spp. in Norway is associated with the acquisition of AAC(3)-II and AAC(6')-Ib. Diagnostic microbiology and infectious disease 2014; Volum 78 (1). ISSN 0732-8893.s 66 - 69.s doi: 10.1016/j.diagmicrobio.2013.10.001.

  • Leiros, Hanna-Kirsti S.; Skagseth, Susann; Edvardsen, Kine Susann Waade; Lorentzen, Marit Sjo; Bjerga, Gro Elin Kjæreng; Leiros, Ingar; Samuelsen, Ørjan. His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7. Antimicrobial Agents and Chemotherapy 2014; Volum 58 (8). ISSN 0066-4804.s 4826 - 4836.s doi: 10.1128/AAC.02735-13.

  • Jørgensen, Silje Bakken; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Bhatti, Sidra Ahmad; Jørgensen, Ingvild Aalberg; Sivapathasundaram, Thusanth; Leegaard, Truls Michael. High prevalence of faecal carriage of ESBL-producing Enterobacteriaceae in Norwegian patients with gastroenteritis. Scandinavian Journal of Infectious Diseases 2014; Volum 46 (6). ISSN 0036-5548.s 462 - 465.s doi: 10.3109/00365548.2014.896031.

  • Tofteland, Ståle; Naseer, Mohammed Umaer; Lislevand, Jan Helge; Sundsfjord, Arnfinn; Samuelsen, Ørjan. A Long-Term Low-Frequency Hospital Outbreak of KPC-Producing Klebsiella pneumoniae Involving Intergenus Plasmid Diffusion and a Persisting Environmental Reservoir. PLOS ONE 2013; Volum 8 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0059015.

  • Nijhuis, Roel; Samuelsen, Ørjan; Savelkoul, Paul; van Zwet, Anton. Evaluation of a new real-time PCR assay (Check-Direct CPE) for rapid detection of KPC, OXA-48, VIM, and NDM carbapenemases using spiked rectal swabs. Diagnostic microbiology and infectious disease 2013; Volum 77 (4). ISSN 0732-8893.s 316 - 320.s doi: 10.1016/j.diagmicrobio.2013.09.007.

  • Nilsen, Einar; Haldorsen, Bjørg; Sundsfjord, Arnfinn; Simonsen, Gunnar Skov; Ingebretsen, André; Naseer, Mohammed Umaer; Samuelsen, Ørjan. Large IncHI2-plasmids encode extended-spectrum beta-lactamases (ESBLs) in Enterobacter spp. bloodstream isolates, and support ESBL-transfer to Escherichia coli. Clinical Microbiology and Infection (CMI) 2013; Volum 19 (11). ISSN 1198-743X.s E516 - E518.s doi: 10.1111/1469-0691.12274.

  • Borra, Naga Pardha Saradhi; Samuelsen, Ørjan; Spencer, James; Walsh, Timothy R.; Lorentzen, marit sjo; Leiros, Hanna-Kirsti S.. Crystal Structures of Pseudomonas aeruginosa GIM-1: Active-Site Plasticity in Metallo-beta-Lactamases. Antimicrobial Agents and Chemotherapy 2013; Volum 57 (2). ISSN 0066-4804.s 848 - 854.s doi: 10.1128/AAC.02227-12.

  • Saule, Mara; Samuelsen, Ørjan; Dumpis, Uga; Sundsfjord, Arnfinn; Karlsone, Aija; Balode, Arta; Miklasevics, Edvins; Karah, Nabil. Dissemination of a Carbapenem-Resistant Acinetobacter baumannii Strain Belonging to International Clone II/Sequence Type 2 and Harboring a Novel AbaR4-Like Resistance Island in Latvia. Antimicrobial Agents and Chemotherapy 2013; Volum 57 (2). ISSN 0066-4804.s 1069 - 1072.s doi: 10.1128/AAC.01783-12.

  • Starikova, Irina; Harms, Klaus; Haugen, Pål; Lunde, Tracy Munthali; Primicerio, Raul; Samuelsen, Ørjan; Nielsen, Kaare Magne; Johnsen, Pål Jarle. A Trade-off between the Fitness Cost of Functional Integrases and Long-trem stability of Integrons. (Fulltekst: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1003043 PLoS Pathogens 2012; Volum 8 (11). ISSN 1553-7366.s doi: 10.1371/journal.ppat.1003043.

  • Karah, Nabil; Sundsfjord, Arnfinn; Towner, Kevin; Samuelsen, Ørjan. Insights into the global molecular epidemiology of carbapenem non-susceptible clones of Acinetobacter baumannii. Drug resistance updates 2012; Volum 15 (4). ISSN 1368-7646.s 237 - 247.s doi: 10.1016/j.drup.2012.06.001.

  • Leiros, Hanna-Kirsti S.; Borra, Naga Pardha Saradhi; Brandsdal, Bjørn Olav; Edvardsen, Kine Susann Waade; Spencer, James; Walsh, Timothy R.; Samuelsen, Ørjan. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157. Antimicrobial Agents and Chemotherapy 2012; Volum 56 (8). ISSN 0066-4804.s 4341 - 4353.s doi: 10.1128/AAC.00448-12.

  • El Salabi, Allaaeddin; Borra, Naga Pardha Saradhi; Toleman, Mark A.; Samuelsen, Ørjan; Walsh, Timothy R.. Genetic and Biochemical Characterization of a Novel Metallo-beta-Lactamase, TMB-1, from an Achromobacter xylosoxidans Strain Isolated in Tripoli, Libya. Antimicrobial Agents and Chemotherapy 2012; Volum 56 (5). ISSN 0066-4804.s 2241 - 2245.s doi: 10.1128/AAC.05640-11.

  • Hansen, Frank; Hammerum, Anette M.; Skov, Robert L; Giske, Christian G.; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Evaluation of Rosco Neo-Sensitabs for phenotypic detection and subgrouping of ESBL-, AmpC- and carbapenemase-producing Enterobacteriaceae. APMIS - Journal of Pathologiy, Microbiology and Immunology 2012; Volum 120 (9). ISSN 0903-4641.s 724 - 732.s doi: 10.1111/j.1600-0463.2012.02898.x.

  • Canton, Rafael; Akova, Murat; Carmeli, Yehuda; Giske, Christian; Glupczynski, Youri; Gniadkowski, Marek; Livermore, David M.; Miriagou, Vivi; Naas, Thiery; Rossolini, Gian Maria; Samuelsen, Ørjan; Seifert, Harald; Woodford, Neil; Nordmann, Patrice. Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe. Clinical Microbiology and Infection (CMI) 2012; Volum 18 (5). ISSN 1198-743X.s 413 - 431.s doi: 10.1111/j.1469-0691.2012.03821.x.

  • Naseer, Mohammed Umaer; Eriksen, Bjørn Odvar; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Fecal colonization of VIM-1-producing Klebsiella pneumoniae and in vivo transfer of multidrug-resistant IncN plasmid in a renal transplant patient. Diagnostic microbiology and infectious disease 2012; Volum 72 (4). ISSN 0732-8893.s 363 - 366.s doi: 10.1016/j.diagmicrobio.2011.12.010.

  • Haldorsen, Bjørg; Samuelsen, Ørjan. Multiresistente Gram-negative bakterier - et økende globalt helseproblem. (Fulltekst: http://viewer.zmags.com/publication/3abcda29#/3abcda29/16 Bioingeniøren 2012; Volum 47 (2). ISSN 0801-6828.s 16 - 21.

  • Karah, Nabil; Giske, Christian G.; Sundsfjord, Arnfinn; Samuelsen, Ørjan. A Diversity of OXA-Carbapenemases and Class 1 Integrons Among Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates from Sweden Belonging to Different International Clonal Lineages. Microbial Drug Resistance 2011; Volum 17 (4). ISSN 1076-6294.s 545 - 549.s doi: 10.1089/mdr.2011.0089.

  • Samuelsen, Ørjan; Toleman, MA; Hasseltvedt, Viggo H; Fuursted, K; Leegaard, Truls Michael; Walsh, TR; Sundsfjord, Arnfinn; Giske, CG. Molecular characterization of VIM-producing Klebsiella pneumoniae from Scandinavia reveals genetic relatedness with international clonal complexes encoding transferable multidrug resistance. Clinical Microbiology and Infection (CMI) 2011; Volum 17 (12). ISSN 1198-743X.s 1811 - 1816.s doi: 10.1111/j.1469-0691.2011.03532.x.

  • Seki, Liliane M.; Pereira, Polyana S.; de Souza, Maria da Penha A. H.; Conceicao, Magda de S.; Marques, Elizabeth A.; Porto, Carlos Oliveira; Colnago, Elvira Maria L.; Alves, Carlene de F. M.; Gomes, Deize; Assef, Ana Paula D. A. Carvalho; Samuelsen, Ørjan; Asensi, Marise D.. Molecular epidemiology of KPC-2-producing Klebsiella pneumoniae isolates in Brazil: the predominance of sequence type 437. Diagnostic microbiology and infectious disease 2011; Volum 70 (2). ISSN 0732-8893.s 274 - 277.s doi: 10.1016/j.diagmicrobio.2011.01.006.

  • Saradhi, Pardha; Leiros, Hanna-Kirsti S.; Ahmad, Rafi; Spencer, James; Leiros, Ingar; Walsh, Timothy R.; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Structural and Computational Investigations of VIM-7: Insights into the Substrate Specificity of VIM Metallo-beta-Lactamases. Journal of Molecular Biology (JMB) 2011; Volum 411 (1). ISSN 0022-2836.s 174 - 189.s doi: 10.1016/j.jmb.2011.05.035.

  • Karah, Nabil; Haldorsen, Bjørg; Hegstad, Kristin; Simonsen, Gunnar Skov; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Species identification and molecular characterization of Acinetobacter spp. blood culture isolates from Norway. Journal of Antimicrobial Chemotherapy 2011; Volum 66 (4). ISSN 0305-7453.s 738 - 744.s doi: 10.1093/jac/dkq521.

  • Karah, Nabil; Haldorsen, Bjørg; Hermansen, Nils Olav; Tveten, Yngvar; Ragnhildstveit, Eivind; Skutlaberg, Dag Harald; Tofteland, Ståle; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Emergence of OXA-carbapenemase- and 16S rRNA methylase-producing international clones of Acinetobacter baumannii in Norway. Journal of Medical Microbiology 2011; Volum 60 (4). ISSN 0022-2615.s 515 - 521.s doi: 10.1099/jmm.0.028340-0.

  • Vading, M; Samuelsen, Ørjan; Haldorsen, Bjørg; Sundsfjord, Arnfinn; Giske, C.G.. Comparison of disk diffusion, Etest and VITEK2 for detection of carbapenemase-producing Klebsiella pneumoniae with the EUCAST and CLSI breakpoint systems. Clinical Microbiology and Infection (CMI) 2011; Volum 17 (5). ISSN 1198-743X.s 668 - 674.s doi: 10.1111/j.1469-0691.2010.03299.x.

  • Giske, C.G.; Gezelius, L; Samuelsen, Ørjan; Warner, M; Sundsfjord, Arnfinn; Woodford, N. A sensitive and specific phenotypic assay for detection of metallo-beta-lactamases and KPC in Klebsiella pneumoniae with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin. Clinical Microbiology and Infection (CMI) 2011; Volum 17 (4). ISSN 1198-743X.s 552 - 556.s doi: 10.1111/j.1469-0691.2010.03294.x.

  • Samuelsen, Ørjan; Toleman, MA; Sundsfjord, Arnfinn; Rydberg, Johan; Leegaard, Truls Michael; Walder, M; Lia, Astrid; Ranheim, Trond Egil; Rajendra, Y; Hermansen, Nils Olav; Walsh, TR; Giske, CG. Molecular Epidemiology of Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa Isolates from Norway and Sweden Shows Import of International Clones and Local Clonal Expansion. Antimicrobial Agents and Chemotherapy 2010; Volum 54 (1). ISSN 0066-4804.s 346 - 352.s doi: 10.1128/AAC.00824-09.

  • Karah, Nabil; Poirel, Laurent; Bengtsson, Stina; Sundqvist, Martin; Kahlmeter, Gunnar; Nordmann, Patrice; Sundsfjord, arnfinn; Samuelsen, Ørjan. Plasmid-mediated quinolone resistance determinants qnr and aac(6 ')-Ib-cr in Escherichia coli and Klebsiella spp. from Norway and Sweden. Diagnostic microbiology and infectious disease 2010; Volum 66 (4). ISSN 0732-8893.s 425 - 431.s doi: 10.1016/j.diagmicrobio.2009.12.004.

  • Samuelsen, Ørjan; Naseer, Umaer; Tofteland, Ståle; Skutlaberg, Dag Harald; Onken, Annette; Hjetland, Reidar; Sundsfjord, Arnfinn; Giske, Christian G.. Emergence of clonally related Klebsiella pneumoniae isolates of sequence type 258 producing plasmid-mediated KPC carbapenemase in Norway and Sweden. Journal of Antimicrobial Chemotherapy 2009; Volum 63 (4). ISSN 0305-7453.s 654 - 658.s doi: 10.1093/jac/dkp018.

  • Samuelsen, Ørjan; Buarø, Liselotte; Toleman, Mark A.; Giske, Christian G.; Hermansen, Nils Olav; Walsh, Timothy R; Sundsfjord, Arnfinn. The first metallo-beta-lactamase identified in Norway is associated with an tniC-class 1 integron in a Pseudomonas aeruginosa isolate of sequence type 233 imported from Ghana. Antimicrobial Agents and Chemotherapy 2009; Volum 53 (1). ISSN 0066-4804.s 331 - 332.

  • Källman, Owe; Giske, Christian G.; Samuelsen, Ørjan; Wretlind, Bengt; Kalin, Mats; Olsson-Liljequist, Barbro. Interplay of Efflux, Impermeability, and AmpC Activity Contributes to Cefuroxime Resistance in Clinical, Non-ESBL-Producing Isolates of Escherichia coli. Microbial Drug Resistance 2009; Volum 15 (2). ISSN 1076-6294.s 91 - 95.s doi: 10.1089/mdr.2009.0883.

  • Ganta, Sudhakar Reddy; Perumal, Senthil; Pagadala, Sundar Ram Reddy; Samuelsen, Ørjan; Spencer, James; Pratt, R.F.; Buynak, John D.. Approaches to the simultaneous inactivation of metallo- and serine-beta-lactamases. Bioorganic & Medicinal Chemistry Letters 2009; Volum 19 (6). ISSN 0960-894X.s 1618 - 1622.s doi: 10.1016/j.bmcl.2009.02.018.

  • Samuelsen, Ørjan; Buarø, Liselotte; Giske, Christian G.; Simonsen, Gunnar Skov; Aasnæs, Bettina; Sundsfjord, arnfinn. Evaluation of phenotypic tests for the detection of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a low prevalence country. Journal of Antimicrobial Chemotherapy 2008; Volum 61. ISSN 0305-7453.s 827 - 830.s doi: 10.1093/jac/dkn016.

  • Samuelsen, Ørjan; Castanheira, Mariana; Walsh, Timothy R; Spencer, James. Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family. Antimicrobial Agents and Chemotherapy 2008; Volum 52 (8). ISSN 0066-4804.s 2905 - 2908.

  • Sundsfjord, Arnfinn; Simonsen, Gunnar Skov; Haldorsen, Bjørg; Lundblad, Eirik Wasmuth; Samuelsen, Ørjan. Bredspektrede betalaktamaser hos gramnegative stavbakterier. Tidsskrift for Den norske legeforening 2008; Volum 128 (23). ISSN 0029-2001.s 2741 - 2745.

  • Vik, Anders; Hedner, Erik; Charnock, Colin; Tangen, Linda; tangen, Linda W; Samuelsen, Ørjan; Larsson, Rolf; Bohlin, Lars; Gundersen, Lise-Lotte. Antimicrobial and cytotoxic activity of agelasine and agelasimine analogs. Bioorganic & Medicinal Chemistry 2007; Volum 15. ISSN 0968-0896.s doi: 10.1016/j.bmc.2007.03.08.

  • Vik, Anders; Hedner, Erik; Charnock, Colin; Samuelsen, Ørjan; Larsson, Rolf; Gundersen, Lise-Lotte; Bohlin, Lars. (+)-agelasine D: Improved synthesis and evaluation of antibacterial and cytotoxic activities. Journal of natural products 2006; Volum 69. ISSN 0163-3864.

  • Samuelsen, Ørjan; Haukland, Hanne; Kahl, BC; Von Eiff, C; Proctor, RA; Ulvatne, H; Sandvik, K; Vorland, Lars. Staphylococcus aureus small colony variants are resistant to the antimicrobial peptide lactoferricin B. Journal of Antimicrobial Chemotherapy 2005; Volum 56 (6). ISSN 0305-7453.s 1126 - 1129.

  • Samuelsen, Ørjan; Haukland, Hanne; Jenssen, Håvard; Kramer, M; Sandvik, K; Ulvatne, Hilde; Vorland, Lars. Induced resistance to the antimicrobial peptide lactoferricin B in Staphylococcus aureus. FEBS Letters 2005; Volum 579. ISSN 0014-5793.

  • Ulvatne, H.; Samuelsen, Ørjan; Haukland, Hanne; Kramer, M; Vorland, Lars. Lactoferricin B inhibits bacterial macromolecular synthesis in Escherichia coli and Bacillus subtilis. FEMS Microbiology Letters 2004; Volum 237. ISSN 0378-1097.s 377 - 384.

  • Ulvatne, Hilde; Haukland, Hanne Husom; Samuelsen, Ørjan; Kramer, Manuela; Vorland, Lars H.. Proteases in Escherichia coli and Staphylococcus aureus confer reduced susceptibility to lactoferricin B. Journal of Antimicrobial Chemotherapy 2002; Volum 50. ISSN 0305-7453.s 461 - 467.

  • Sørum, Vidar; Sollied Møller, Anna; Johnsen, Pål Jarle; Samuelsen, Ørjan; Abel, Sören; Podnecky, Nicole L.. Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains. Annual IBA meeting 2019-11-04 - 2019-11-05 2019.

  • Sørum, Vidar; Sollied Møller, Anna; Abel, Sören; Samuelsen, Ørjan; Podnecky, Nicole L.; Johnsen, Pål Jarle. Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains. Frampeik 2019-10-11 - 2019-10-13 2019.

  • Frøhlich, Christopher; Johnsen, Pål Jarle; Schrøder Leiros, Hanna-Kirsti; Samuelsen, Ørjan. Evolution of OXA-48 under sub-MIC conditions. 3rd Annual Meeting of the National Graduate School in Infection Biology and and Antimicrobials 2019-11-05 - 2019-11-06 2019.

  • Sørum, Vidar; Øynes, Emma Lu; Møller, Anna; Podnecky, Nicole L.; Abel, Sören; Samuelsen, Ørjan; Johnsen, Pål Jarle. Evolutionary stability of collateral susceptibility networks in clinical Escherichia coli strains. ECCMID 2019 2019-04-13 - 2019.

  • Frøhlich, Christopher; Leiros, Hanna-Kirsti S.; Johnsen, Pål Jarle; Samuelsen, Ørjan. Sub-inhibitory concentrations of ceftazidime drive evolution of the OXA-48 carbapenemase. ECCMID 2019 2019-04-13 - 2019-04-16 2019.

  • Kloos, Julia Maria; Alves Gama, Joao Pedro; Samuelsen, Ørjan; Johnsen, Pål Jarle. Plasmid-host co-evolution of Klebsiella pneumoniae MDR-encoding plasmids in clinical isolates of uropathogenic Escherichia coli: effect on fitness cost of plasmid-mediated resistance. IBA Annual Meeting 2018-11-08 - 2018.

  • Kloos, Julia Maria; Alves Gama, Joao Pedro; Samuelsen, Ørjan; Johnsen, Pål Jarle. Klebsiella pneumoniae MDR-encoding plasmids in clinical isolates of uropathogenic Escherichia coli: plasmid-host co-evolution and its effect on fitness cost of plasmid-mediated resistance. Plasmid Biology Symposium 2018-08-05 - 2018-08-10 2018.

  • Frøhlich, Christopher; Sørum, Vidar; Leiros, Hanna-Kirsti S.; Johnsen, Pål Jarle; Samuelsen, Ørjan. Development of OXA-48 mediated ceftazidme-avibactam resistance is associated with an evolutionary trade-off. ECCMID 2018-04-24 - 2018.

  • Jakovljev, Aleksandra; Afset, Jan Egil; Haugum, Kjersti; Rønning, Torunn Gresdal; Steinum, Harald Otto; Samuelsen, Ørjan; Gabrielsen, Christina. "Escherichia coli sepsis: casus presentasjon med uvanlig resistensmønster". Vårmøtet 2018 Norsk Forening for Medisinsk mikrobiologi 2018-05-31 - 2018-06-01 2018.

  • Heikal, Adam; Samuelsen, Ørjan; Kristensen, Tom; Økstad, Ole Andreas Løchen. Complete genome sequence of a multidrug-resistant, blaNDM-1-expressing Klebsiella pneumoniae K66-45 clinical isolate from Norway. Microbiology Resource Announcements (MRA) 2017; Volum 5:e00601 (27). ISSN 2169-8287.s 1 - 2.s doi: 10.1128/genomeA.00601-17.

  • Lund, Bjarte Aarmo; Leiros, Hanna-Kirsti S.; Bayer, Annette; Samuelsen, Ørjan; Christopeit, Tony. The OXA-class of β-lactamases. A structural view on antibiotic resistance. 2017 ISBN 978-82-8236-269-6.

  • Jakovljev, Aleksandra; Afset, Jan Egil; Haugum, Kjersti; Steinum, Harald Otto; Rønning, Torunn Gresdal; Samuelsen, Ørjan; Gabrielsen, Christina. Genetic basis of growth characteristics and trimethoprim-sulfamethoxazole susceptibility of thymine-dependent and thymine-independent serial blood culture isolates of Escherichia coli. 27th ECCMID 2017, 22-25 April, Vienna, Austria 2017-04-22 - 2017-04-25 2017.

  • Jakovljev, Aleksandra; Afset, Jan Egil; Haugum, Kjersti; Steinum, Harald Otto; Rønning Gresdal, Torunn; Samuelsen, Ørjan; Gabrielsen, Christina. Undersøkelse av det genetiske grunnlaget for fenotypiske forskjeller i vekstegenskaper og følsomhet overfor trimetoprim-sulfamethoxazole hos Escherichia coli isolert fra pasient med residiverende bakteriemiepisoder. Årskonferanse FHI 2016 2016-12-01 - 2016-12-02 2016.

  • Onarheim, Henning; BREKKE, RAGNVALD LJONES; Leiva, Rafael Alexander Mo; Oma, Dorthea Hagen; Kolstad, Helge; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Mylvaganam, Haima. H. Onarheim og medarbeidere svarer. Tidsskrift for Den norske legeforening 2016; Volum 136 (17). ISSN 0029-2001.s 1424 - 1425.s doi: 10.4045/tidsskr.16.0755.

  • Di Luca, Maria Chiara; Skaare, Dagfinn; Aasnæs, Bettina; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Identification of a novel IMI carbapenemase variant (IMI-9) in Enterobacter cloacae complex. International Journal of Antimicrobial Agents 2016; Volum 48 (6). ISSN 0924-8579.s 764 - 765.s doi: 10.1016/j.ijantimicag.2016.09.004.

  • Onarheim, Henning; Brekke, Ragnvald Ljones; Leiva, Rafael Alexander Mo; Oma, Dorthea Hagen; Kolstad, Helge; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Mylvaganam, Haima. En kvinne med sepsis etter brannskade i Pakistan. Tidsskrift for Den norske legeforening 2016; Volum 136 (14). ISSN 0029-2001.s 1228 - 1232.

  • Skagseth, Susann; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The impact of residues 119 and 228 in the Tripoli metallo-beta-lactamase TMB-1 involved in resistance to beta-lactam antibiotics. 52nd Norwegian Biochemical Society Contact Meeting, Tromsø 2016-01-21 - 2016-01-24 2016.

  • Hegstad, Kristin; Samuelsen, Ørjan; Hegstad, Joachim; Sundsfjord, Arnfinn. Molecular methods for detection of antibacterial resistance genes: rationale and applications. Wolters Kluwer 2015 ISBN 978-1-4511-7675-9.s 408 - 449.

  • Åstrand, Ove Alexander Høgmoen; Leiros, Hanna-Kirsti S.; Samuelsen, Ørjan; Bayer, Annette; Rongved, Pål. Overcoming b-lactam resistance - A potential solution to multi-drug resistant bacteria. Organisk Kjemisk Vintermøte 2015 2015-01-08 - 2015-01-11 2015.

  • Berg, Einar Sverre; Wester, Astrid Lousie; Mo, Solveig Sølverød; Slettemeås, Jannice Schau; Steinbakk, Martin; Dahle, Ulf R; Samuelsen, Ørjan; Simonsen, Gunnar Skov; Löhr, Iren Høyland; Jørgensen, Silje; Sunde, Marianne. Highly similar cephalosporin resistant Escherichia coli and AmpC resistance plasmids found in both patients and poultry meat in Norway. ECCMID 2015-04-25 - 2015-04-28 2015.

  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The fight against metallo-beta-lactamases and antibiotic resistance. Annual BioStruct Conference, The National graduate school in structural biology 2015-09-27 - 2015-09-30 2015.

  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The fight against metallo-beta-lactamases and antibiotic resistance. BioStruct Open Day 2015-03-20 - 2015-03-20 2015.

  • Christopeit, Tony; Carlsen, Trine Josefine Olsen; Skagseth, Susann; Lund, Bjarte Aarmo; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Using fragment screening to identify novel starting points for potent inhibitors of metallo-beta-lactamase VIM-2. Fragments 2015: Fifth RSC-BMCS Fragment-based Drug Discovery meeting 2015-03-22 - 2015-03-22 2015.

  • Christopeit, Tony; Lund, Bjarte Aarmo; Carlsen, Trine Josefine Olsen; Skagseth, Susann; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Using Fragment Screening to Identify Novel Starting Points for Potent Carbapenemase Inhibitors. Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) 2015-09-17 - 2015-09-21 2015.

  • Paulsen, Marianne H.; Engqvist, Stig Olov Magnus; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.; Skagseth, Susann; Leszczak, Kinga; Akhter, Sundus; Bayer, Annette. Synthesis of potential metallo-beta-lactamase inhibitors. Organisk kjemisk vintermøte OKV29 2014-01-09 - 2014-01-12 2014.

  • Hansen, Frank; Hammerum, Anette M.; Skov, Robert; Haldorsen, Bjørg; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Evaluation of the total MBL confirm kit (ROSCO) for detection of metallo-β-lactamases in Pseudomonas aeruginosa and Acinetobacter baumannii. Diagnostic microbiology and infectious disease 2014; Volum 79 (4). ISSN 0732-8893.s 486 - 488.s doi: 10.1016/j.diagmicrobio.2013.12.001.

  • Lund, Bjarte Aarmo; Bjerga, Gro Elin Kjæreng; Christopeit, Tony; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Structural view on antibiotic resistance. Fragment-based lead discovery for the inhibition of oxacillinases. 12th Beta-Lactamase Meeting 2014-06-28 - 2014-07-01 2014.

  • Lund, Bjarte Aarmo; Bjerga, Gro Elin Kjæreng; Christopeit, Tony; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Structural view on antibiotic resistance. Fragment-based lead discovery for the inhibition of oxacillinases. The 46th INTERNATIONAL SCHOOL OF CRYSTALLOGRAPHY 2014-05-30 - 2014-06-08 2014.

  • Christopeit, Tony; Carlsen, Trine Josefine Olsen; Skagseth, Susann; Lund, Bjarte Aarmo; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Characterization of substrate and inhibitor binding to different beta-lactamases using Surface Plasmon Resonance based biosensors. 12th Beta-Lactamase Meeting 2014-06-28 - 2014-07-01 2014.

  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Bjerga, Gro Elin Kjæreng; Bayer, Annette; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The importance of residue Trp228 and Tyr233 in the metallo-beta-lactamase GIM-1. 12th Beta-Lactamase Meeting 2014-06-28 - 2014-07-01 2014.

  • Haldorsen, Bjørg; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Hegstad, Kristin. Agreement of the MIC Test Strip and Etest with microbroth dilution in glycopeptide susceptibility testing of Enterococcus sp. 23rd European Congress of Clinical Microbiology and Infectious Diseases 2013-04-27 - 2013-04-30 2013.

  • Samuelsen, Ørjan; Naseer, Mohammed Umaer; Karah, Nabil; Lindemann, Paul Christoffer; Leegaard, Truls Michael; Sundsfjord, Arnfinn; Kanestrøm, Anita. Identification of Enterobacteriaceae isolates with OXA-48 and coproduction of OXA-181 and NDM-1 in Norway. Journal of Antimicrobial Chemotherapy 2013; Volum 68 (7). ISSN 0305-7453.s 1682 - 1685.s doi: 10.1093/jac/dkt058.

  • Sundsfjord, Arnfinn; Samuelsen, Ørjan; Hegstad, Kristin; Haldorsen, Bjørg C. I førstelinjen mot resistente bakterier. Bioingeniøren 2012 (2). ISSN 0801-6828.s 12 - 14.

  • Dahle, Ulf R; Wester, Astrid Louise; Samuelsen, Ørjan; Sundsfjord, Arnfinn. Siste skanse for effektive antibiotika?. Tidsskrift for Den norske legeforening 2012; Volum 132. ISSN 0029-2001.s 1725 - 1726.s doi: 10.4045/tidsskr.12.0565.

  • Samuelsen, Ørjan; Thilesen, Carina; Heggelund, Lars; Vada, Anne N.; Kümmel, Angela; Sundsfjord, arnfinn. Identification of NDM-1-producing Enterobacteriaceae in Norway. Journal of Antimicrobial Chemotherapy 2011; Volum 66 (3). ISSN 0305-7453.s 670 - 672.s doi: 10.1093/jac/dkq483.

  • Tveten, Yngvar; Sarjomaa, Marjut Anneli; Skaare, Dagfinn; Grude, Nils; Samuelsen, Ørjan. Hvordan stoppe multiresidente bakterier?. Tidsskrift for Den norske legeforening 2011; Volum 7 (131). ISSN 0029-2001.s 698 - 700.s doi: 10.4045/tidsskr.10.0369.

  • Samuelsen, Ørjan. Resistance to the antimicrobial peptide lactoferricin B in Staphylococcus aureus. 2005 ISBN 82-7589-156-6.

  • Sørum, Vidar; Sollied Møller, Anna; Johnsen, Pål Jarle; Samuelsen, Ørjan; Abel, Sören; Podnecky, Nicole L.. Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains. Annual IBA meeting 2019-11-04 - 2019-11-05 2019.

  • Sørum, Vidar; Sollied Møller, Anna; Abel, Sören; Samuelsen, Ørjan; Podnecky, Nicole L.; Johnsen, Pål Jarle. Evolutionary stability of collateral effects in ciprofloxacin resistant clinical Escherichia coli strains. Frampeik 2019-10-11 - 2019-10-13 2019.

  • Frøhlich, Christopher; Johnsen, Pål Jarle; Schrøder Leiros, Hanna-Kirsti; Samuelsen, Ørjan. Evolution of OXA-48 under sub-MIC conditions. 3rd Annual Meeting of the National Graduate School in Infection Biology and and Antimicrobials 2019-11-05 - 2019-11-06 2019.

  • Sørum, Vidar; Øynes, Emma Lu; Møller, Anna; Podnecky, Nicole L.; Abel, Sören; Samuelsen, Ørjan; Johnsen, Pål Jarle. Evolutionary stability of collateral susceptibility networks in clinical Escherichia coli strains. ECCMID 2019 2019-04-13 - 2019.

  • Frøhlich, Christopher; Leiros, Hanna-Kirsti S.; Johnsen, Pål Jarle; Samuelsen, Ørjan. Sub-inhibitory concentrations of ceftazidime drive evolution of the OXA-48 carbapenemase. ECCMID 2019 2019-04-13 - 2019-04-16 2019.

  • Kloos, Julia Maria; Alves Gama, Joao Pedro; Samuelsen, Ørjan; Johnsen, Pål Jarle. Plasmid-host co-evolution of Klebsiella pneumoniae MDR-encoding plasmids in clinical isolates of uropathogenic Escherichia coli: effect on fitness cost of plasmid-mediated resistance. IBA Annual Meeting 2018-11-08 - 2018.

  • Kloos, Julia Maria; Alves Gama, Joao Pedro; Samuelsen, Ørjan; Johnsen, Pål Jarle. Klebsiella pneumoniae MDR-encoding plasmids in clinical isolates of uropathogenic Escherichia coli: plasmid-host co-evolution and its effect on fitness cost of plasmid-mediated resistance. Plasmid Biology Symposium 2018-08-05 - 2018-08-10 2018.

  • Frøhlich, Christopher; Sørum, Vidar; Leiros, Hanna-Kirsti S.; Johnsen, Pål Jarle; Samuelsen, Ørjan. Development of OXA-48 mediated ceftazidme-avibactam resistance is associated with an evolutionary trade-off. ECCMID 2018-04-24 - 2018.

  • Jakovljev, Aleksandra; Afset, Jan Egil; Haugum, Kjersti; Rønning, Torunn Gresdal; Steinum, Harald Otto; Samuelsen, Ørjan; Gabrielsen, Christina. "Escherichia coli sepsis: casus presentasjon med uvanlig resistensmønster". Vårmøtet 2018 Norsk Forening for Medisinsk mikrobiologi 2018-05-31 - 2018-06-01 2018.

  • Heikal, Adam; Samuelsen, Ørjan; Kristensen, Tom; Økstad, Ole Andreas Løchen. Complete genome sequence of a multidrug-resistant, blaNDM-1-expressing Klebsiella pneumoniae K66-45 clinical isolate from Norway. Microbiology Resource Announcements (MRA) 2017; Volum 5:e00601 (27). ISSN 2169-8287.s 1 - 2.s doi: 10.1128/genomeA.00601-17.

  • Lund, Bjarte Aarmo; Leiros, Hanna-Kirsti S.; Bayer, Annette; Samuelsen, Ørjan; Christopeit, Tony. The OXA-class of β-lactamases. A structural view on antibiotic resistance. 2017 ISBN 978-82-8236-269-6.

  • Jakovljev, Aleksandra; Afset, Jan Egil; Haugum, Kjersti; Steinum, Harald Otto; Rønning, Torunn Gresdal; Samuelsen, Ørjan; Gabrielsen, Christina. Genetic basis of growth characteristics and trimethoprim-sulfamethoxazole susceptibility of thymine-dependent and thymine-independent serial blood culture isolates of Escherichia coli. 27th ECCMID 2017, 22-25 April, Vienna, Austria 2017-04-22 - 2017-04-25 2017.

  • Jakovljev, Aleksandra; Afset, Jan Egil; Haugum, Kjersti; Steinum, Harald Otto; Rønning Gresdal, Torunn; Samuelsen, Ørjan; Gabrielsen, Christina. Undersøkelse av det genetiske grunnlaget for fenotypiske forskjeller i vekstegenskaper og følsomhet overfor trimetoprim-sulfamethoxazole hos Escherichia coli isolert fra pasient med residiverende bakteriemiepisoder. Årskonferanse FHI 2016 2016-12-01 - 2016-12-02 2016.

  • Onarheim, Henning; BREKKE, RAGNVALD LJONES; Leiva, Rafael Alexander Mo; Oma, Dorthea Hagen; Kolstad, Helge; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Mylvaganam, Haima. H. Onarheim og medarbeidere svarer. Tidsskrift for Den norske legeforening 2016; Volum 136 (17). ISSN 0029-2001.s 1424 - 1425.s doi: 10.4045/tidsskr.16.0755.

  • Di Luca, Maria Chiara; Skaare, Dagfinn; Aasnæs, Bettina; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Identification of a novel IMI carbapenemase variant (IMI-9) in Enterobacter cloacae complex. International Journal of Antimicrobial Agents 2016; Volum 48 (6). ISSN 0924-8579.s 764 - 765.s doi: 10.1016/j.ijantimicag.2016.09.004.

  • Onarheim, Henning; Brekke, Ragnvald Ljones; Leiva, Rafael Alexander Mo; Oma, Dorthea Hagen; Kolstad, Helge; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Mylvaganam, Haima. En kvinne med sepsis etter brannskade i Pakistan. Tidsskrift for Den norske legeforening 2016; Volum 136 (14). ISSN 0029-2001.s 1228 - 1232.

  • Skagseth, Susann; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The impact of residues 119 and 228 in the Tripoli metallo-beta-lactamase TMB-1 involved in resistance to beta-lactam antibiotics. 52nd Norwegian Biochemical Society Contact Meeting, Tromsø 2016-01-21 - 2016-01-24 2016.

  • Hegstad, Kristin; Samuelsen, Ørjan; Hegstad, Joachim; Sundsfjord, Arnfinn. Molecular methods for detection of antibacterial resistance genes: rationale and applications. Wolters Kluwer 2015 ISBN 978-1-4511-7675-9.s 408 - 449.

  • Åstrand, Ove Alexander Høgmoen; Leiros, Hanna-Kirsti S.; Samuelsen, Ørjan; Bayer, Annette; Rongved, Pål. Overcoming b-lactam resistance - A potential solution to multi-drug resistant bacteria. Organisk Kjemisk Vintermøte 2015 2015-01-08 - 2015-01-11 2015.

  • Berg, Einar Sverre; Wester, Astrid Lousie; Mo, Solveig Sølverød; Slettemeås, Jannice Schau; Steinbakk, Martin; Dahle, Ulf R; Samuelsen, Ørjan; Simonsen, Gunnar Skov; Löhr, Iren Høyland; Jørgensen, Silje; Sunde, Marianne. Highly similar cephalosporin resistant Escherichia coli and AmpC resistance plasmids found in both patients and poultry meat in Norway. ECCMID 2015-04-25 - 2015-04-28 2015.

  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The fight against metallo-beta-lactamases and antibiotic resistance. Annual BioStruct Conference, The National graduate school in structural biology 2015-09-27 - 2015-09-30 2015.

  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Akhter, Sundus; Zeeshan, Muhammad; Åstrand, Ove Alexander Høgmoen; Bayer, Annette; Rongved, Pål; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The fight against metallo-beta-lactamases and antibiotic resistance. BioStruct Open Day 2015-03-20 - 2015-03-20 2015.

  • Christopeit, Tony; Carlsen, Trine Josefine Olsen; Skagseth, Susann; Lund, Bjarte Aarmo; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Using fragment screening to identify novel starting points for potent inhibitors of metallo-beta-lactamase VIM-2. Fragments 2015: Fifth RSC-BMCS Fragment-based Drug Discovery meeting 2015-03-22 - 2015-03-22 2015.

  • Christopeit, Tony; Lund, Bjarte Aarmo; Carlsen, Trine Josefine Olsen; Skagseth, Susann; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Using Fragment Screening to Identify Novel Starting Points for Potent Carbapenemase Inhibitors. Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC) 2015-09-17 - 2015-09-21 2015.

  • Paulsen, Marianne H.; Engqvist, Stig Olov Magnus; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.; Skagseth, Susann; Leszczak, Kinga; Akhter, Sundus; Bayer, Annette. Synthesis of potential metallo-beta-lactamase inhibitors. Organisk kjemisk vintermøte OKV29 2014-01-09 - 2014-01-12 2014.

  • Hansen, Frank; Hammerum, Anette M.; Skov, Robert; Haldorsen, Bjørg; Sundsfjord, Arnfinn; Samuelsen, Ørjan. Evaluation of the total MBL confirm kit (ROSCO) for detection of metallo-β-lactamases in Pseudomonas aeruginosa and Acinetobacter baumannii. Diagnostic microbiology and infectious disease 2014; Volum 79 (4). ISSN 0732-8893.s 486 - 488.s doi: 10.1016/j.diagmicrobio.2013.12.001.

  • Lund, Bjarte Aarmo; Bjerga, Gro Elin Kjæreng; Christopeit, Tony; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Structural view on antibiotic resistance. Fragment-based lead discovery for the inhibition of oxacillinases. 12th Beta-Lactamase Meeting 2014-06-28 - 2014-07-01 2014.

  • Lund, Bjarte Aarmo; Bjerga, Gro Elin Kjæreng; Christopeit, Tony; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Structural view on antibiotic resistance. Fragment-based lead discovery for the inhibition of oxacillinases. The 46th INTERNATIONAL SCHOOL OF CRYSTALLOGRAPHY 2014-05-30 - 2014-06-08 2014.

  • Christopeit, Tony; Carlsen, Trine Josefine Olsen; Skagseth, Susann; Lund, Bjarte Aarmo; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. Characterization of substrate and inhibitor binding to different beta-lactamases using Surface Plasmon Resonance based biosensors. 12th Beta-Lactamase Meeting 2014-06-28 - 2014-07-01 2014.

  • Skagseth, Susann; Carlsen, Trine Josefine Olsen; Bjerga, Gro Elin Kjæreng; Bayer, Annette; Samuelsen, Ørjan; Leiros, Hanna-Kirsti S.. The importance of residue Trp228 and Tyr233 in the metallo-beta-lactamase GIM-1. 12th Beta-Lactamase Meeting 2014-06-28 - 2014-07-01 2014.

  • Haldorsen, Bjørg; Samuelsen, Ørjan; Sundsfjord, Arnfinn; Hegstad, Kristin. Agreement of the MIC Test Strip and Etest with microbroth dilution in glycopeptide susceptibility testing of Enterococcus sp. 23rd European Congress of Clinical Microbiology and Infectious Diseases 2013-04-27 - 2013-04-30 2013.

  • Samuelsen, Ørjan; Naseer, Mohammed Umaer; Karah, Nabil; Lindemann, Paul Christoffer; Leegaard, Truls Michael; Sundsfjord, Arnfinn; Kanestrøm, Anita. Identification of Enterobacteriaceae isolates with OXA-48 and coproduction of OXA-181 and NDM-1 in Norway. Journal of Antimicrobial Chemotherapy 2013; Volum 68 (7). ISSN 0305-7453.s 1682 - 1685.s doi: 10.1093/jac/dkt058.

  • Sundsfjord, Arnfinn; Samuelsen, Ørjan; Hegstad, Kristin; Haldorsen, Bjørg C. I førstelinjen mot resistente bakterier. Bioingeniøren 2012 (2). ISSN 0801-6828.s 12 - 14.

  • Dahle, Ulf R; Wester, Astrid Louise; Samuelsen, Ørjan; Sundsfjord, Arnfinn. Siste skanse for effektive antibiotika?. Tidsskrift for Den norske legeforening 2012; Volum 132. ISSN 0029-2001.s 1725 - 1726.s doi: 10.4045/tidsskr.12.0565.

  • Samuelsen, Ørjan; Thilesen, Carina; Heggelund, Lars; Vada, Anne N.; Kümmel, Angela; Sundsfjord, arnfinn. Identification of NDM-1-producing Enterobacteriaceae in Norway. Journal of Antimicrobial Chemotherapy 2011; Volum 66 (3). ISSN 0305-7453.s 670 - 672.s doi: 10.1093/jac/dkq483.

  • Tveten, Yngvar; Sarjomaa, Marjut Anneli; Skaare, Dagfinn; Grude, Nils; Samuelsen, Ørjan. Hvordan stoppe multiresidente bakterier?. Tidsskrift for Den norske legeforening 2011; Volum 7 (131). ISSN 0029-2001.s 698 - 700.s doi: 10.4045/tidsskr.10.0369.

  • Samuelsen, Ørjan. Resistance to the antimicrobial peptide lactoferricin B in Staphylococcus aureus. 2005 ISBN 82-7589-156-6.

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