Johan Isaksson.jpg
Photo: UiT
Johan Isaksson.jpg
Kemiija instituhtta johan.isaksson@uit.no +4777644842 41354726 Tromsø REALF C 206.2

Isaksson, Johan Mattias



  • Olsen, Elisabeth; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer. Antioxidant effect of four bromophenols from the red algae Vertebrata lanosa. Planta Medica 2012; Volum 78 (11). ISSN 0032-0943.s 1146 - 1146.
  • Kovacs, H; Agback, T; Isaksson, Johan. Probing water-protein contacts in a MMP-12/CGS27023A complex by nuclear magnetic resonance spectroscopy. Journal of Biomolecular NMR 2012; Volum 53 (2). ISSN 0925-2738.s 85 - 92.s doi: 10.1007/s10858-012-9624-7.
  • Tørfoss, Veronika; Isaksson, Johan; Ausbacher, Dominik; Brandsdal, Bjørn Olav; Flaten, Gøril Eide; Anderssen, Trude; Cavalcanti Jacobsen, Cristiane de Albuquerque; Havelkova, Martina; Nguyen, Leonard T.; Vogel, Hans J.; Strøm, Morten B.. Improved anticancer potency by head-to-tail cyclization of short cationic anticancer peptides containing a lipophilic b2,2-amino acid. Journal of Peptide Science 2012; Volum 18 (10). ISSN 1075-2617.s 609 - 619.s doi: 10.1002/psc.2441.
  • Isaksson, Johan; Brandsdal, Bjørn Olav; Engqvist, Stig Olov Magnus; Flaten, Gøril Eide; Svendsen, John Sigurd; Stensen, Wenche. A Synthetic Antimicrobial Peptidomimetic (LTX 109): Stereochemical Impact on Membrane Disruption. Journal of Medicinal Chemistry 2011; Volum 54 (16). ISSN 0022-2623.s 5786 - 5795.s doi: 10.1021/jm200450h.
  • Isaksson, Johan; Flaten, Gøril Eide; Brandsdal, Bjørn Olav; Svendsen, John Sigurd. Studies of Small Synthetic Anti-microbial Peptides by NMR and Molecular Modeling. Joint EUROMAR 2010 + ISMAR 2010 2010-07-05 - 2010-07-09 2010.
  • Isaksson, Johan; Nyström, Susanne; Derbyshire, Dean; Wallberg, Hans; Agback, Tatiana; Kovacs, Helena; Bertini, Ivano; Giachetti, Andrea; Luchinat, Claudio. Does a Fast Nuclear Magnetic Resonance Spectroscopy- and X-Ray Crystallography Hybrid Approach Provide Reliable Structural Information of Ligand-Protein Complexes? A Case Study of Metalloproteinases. Journal of Medicinal Chemistry 2009; Volum 52. ISSN 0022-2623.s 1712 - 1722.s doi: 10.1021/jm801388q.
  • Isaksson, Johan; Chattopadhyaya, Jyoti. A Uniform Mechanism Correlating Dangling-End Stabilization and Stacking Geometry. Biochemistry 2005; Volum 44. ISSN 0006-2960.s 5390 - 5401.s doi: 10.1021/bi047414f.
  • Isaksson, Johan; Plashkevych, Oles; Pradeepkumar, P. I.; Chatterjee, S.; Barman, J.; Pathmasiri, W.; Shrivastava, P.; Petit, Catherine; Chattopadhyaya, Jyoti. Oxetane Locked Thymidine in the Dickerson-Drew Dodecamer Causes Local Base Pairing Distortions - An NMR Structure and Hydration Study. Journal of Biomolecular Structure and Dynamics 2005; Volum 23 (3). ISSN 0739-1102.s 299 - 330.
  • Isaksson, Johan; Acharya, Sandipta; Barman, J.; Cheruku, Pradeep; Chattopadhyaya, Jyoti. Single-Stranded Adenine-Rich DNA and RNA Retain Structural Characteristics of Their Respective Double-Stranded Conformations and Show Directional Differences in Stacking Pattern. Biochemistry 2004; Volum 43. ISSN 0006-2960.s 15996 - 16010.s doi: 10.1021/bi048221v.
  • Acharya, Sandipta; Barman, Jharna; Cheruku, Pradeep; Chatterjee, Subhrangsu; Acharya, Parag; Isaksson, Johan; Chattopadhyaya, Jyoti. Significant pKa Perturbation of Nucleobases Is an Intrinsic Property of the Sequence Context of DNA and RNA. Journal of the American Chemical Society 2004; Volum 126. ISSN 0002-7863.s 8674 - 8681.s doi: 10.1021/ja048484c.
  • Boon, Elizabeth M.; Barton, Jacqueline K.; Pradeepkumar, P. I.; Isaksson, Johan; Petit, Catherine; Chattopadhyaya, Jyoti. An Electrochemical Probe of DNA Stacking in an Antisense Oligonucleotide Containing a C3'-endo-Locked Sugar. Angewandte Chemie International Edition 2002; Volum 41 (8). ISSN 1433-7851.s 3402 - 3405.
  • Isaksson, Johan; Zamaratski, Edouard; Maltseva, Tatiana; Agback, Peter; Kumar, A.; Chattopadhyaya, Jyoti. The First Example of a Hoogsteen Basepaired DNA Duplex in Dynamic Equilibrium with a Watson-Crick Basepaired Duplex - A Structural (NMR), Kinetic and Thermodynamic Study. Journal of Biomolecular Structure and Dynamics 2001; Volum 18 (6). ISSN 0739-1102.s 783 - 806.
  • Zamaratski, Edouard; Trifonova, Anna; Acharya, Parag; Isaksson, Johan; Maltseva, Tatiana; Chattopadhyaya, Jyoti. Do the 16-mer, 5'-GUGGUCUGAUGAGGCC-3' and the 25-mer, 5'-GGCCGAAACUCGUAAGAGUCACCAC-3', Form a Hammerhead Ribozyme Structure in Physiological Conditions? An NMR and UV Thermodynamic Study. Nucleosides, Nucleotides & Nucleic Acids 2001; Volum 20. ISSN 1525-7770.s 1219 - 1223.
  • Isaksson, Johan; Maltseva, Tatiana; Agback, Peter; Luo, X.; Kumar, A; Zamaratski, Edouard; Chattopadhyaya, Jyoti. A Single Carbocyclic Nucleotide Substitution in a 12mer DNA Gives a Hoogsteen Basepaired Duplex (Till 38°C) and a Hairpin (Till 65°C). A 600 MHz NMR Spectroscopic Study. Nucleosides, Nucleotides & Nucleic Acids 1999; Volum 18. ISSN 1525-7770.s 1593 - 1596.
    • Juskewitz, Eric; Mishchenko, Ekaterina; Dubey, Vishesh Kumar; Jenssen, Marte; Jakubec, Martin; Rainsford, Philip; Isaksson, Johan Mattias; Andersen, Jeanette Hammer; Ericson, Johanna U. Lulworthinone: In Vitro Mode of Action Investigation of an Antibacterial Dimeric Naphthopyrone Isolated from a Marine Fungus. Marine Drugs 2022. ISSN 1660-3397.s doi: 10.3390/md20050277.
    • Rainsford, Philip Ben; Sarre, Birta R.; Falavigna, Margherita; Brandsdal, Bjørn Olav; Flaten, Gøril Eide; Jakubec, Martin; Isaksson, Johan Mattias. WIND-PVPA: Water/Ion NMR Detected PVPA to assess lipid barrier integrity in vitro through quantification of passive water- and ion transport. Biochimica et Biophysica Acta - Biomembranes 2022; Volum 1864 (7). ISSN 0005-2736.s doi: 10.1016/j.bbamem.2022.183911.
    • Jenssen, Marte; Kristoffersen, Venke; Motiram-Corral, Kumar; Isaksson, Johan; Rämä, Teppo; Andersen, Jeanette Hammer; Hansen, Espen; Østnes Hansen, Kine. Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina. Molecules 2021; Volum 26 (24). ISSN 1420-3049.s doi: 10.3390/molecules26247560.
    • Jenssen, Marte; Rainsford, Philip; Juskewitz, Eric; Andersen, Jeanette Hammer; Hansen, Espen; Isaksson, Johan; Rämä, Teppo; Østnes Hansen, Kine. Lulworthinone, a New Dimeric Naphthopyrone From a Marine Fungus in the Family Lulworthiaceae With Antibacterial Activity Against Clinical Methicillin-Resistant Staphylococcus aureus Isolates. Frontiers in Microbiology 2021; Volum 12. ISSN 1664-302X.s doi: 10.3389/fmicb.2021.730740.
    • Kristoffersen, Venke; Jenssen, Marte; Jawad, Heba Raid; Isaksson, Johan; Hansen, Espen; Rämä, Teppo; Østnes Hansen, Kine; Andersen, Jeanette Hammer. Two Novel Lyso-Ornithine Lipids Isolated from an Arctic Marine Lacinutrix sp. Bacterium. Molecules 2021; Volum 26 (17). ISSN 1420-3049.s doi: 10.3390/molecules26175295.
    • Paulsen, Marianne Hagensen; Engqvist, Magnus; Ausbacher, Dominik; Anderssen, Trude; Langer, Manuel K-; Haug, Tor; Morello, Glenn Robert; Liikanen, Laura; Blencke, Hans-Matti; Isaksson, Johan; Juskewitz, Eric; Bayer, Annette; Strøm, Morten B.. Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates. Journal of Medicinal Chemistry 2021; Volum 64 (15). ISSN 0022-2623.s 11395 - 11417.s doi: 10.1021/acs.jmedchem.1c00734.
    • Dinku, Worku; Isaksson, Johan; Rylandsholm, Fredrik G.; Bouř, Petr; Brichtova, Eva; Choi, Sang Un; Lee, Sang-Ho; Jung, Young-Sik; No, Zae Sung; Svendsen, John Sigurd Mjøen; Aasen, Arne Jørgen; Dekebo, Aman. Anti-proliferative activity of a novel tricyclic triterpenoid acid from Commiphora africana resin against four human cancer cell lines. Applied Biological Chemistry 2020; Volum 63 (1). ISSN 2468-0834.s 16 - 27.s doi: 10.1186/s13765-020-00499-w.
    • Guttormsen, Yngve; Fairhurst, Magnus John Espeland; Pandey, Sunil Kumar; Isaksson, Johan; Haug, Bengt Erik; Bayer, Annette. Total synthesis of phorbazole B. (prosjekt) Molecules 2020; Volum 25 (20). ISSN 1420-3049.s 1 - 10.s doi: 10.3390/molecules25204848.
    • Ndukwe, Ikenna E.; Lam, Yu-hong; Pandey, Sunil Kumar; Haug, Bengt Erik; Bayer, Annette; Sherer, Edward C.; Blinov, Kirill A.; Williamson, R. Thomas; Isaksson, Johan; Reibarkh, Mikhail; Liu, Yizhou; Martin, Gary E.. Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements. Chemical Science 2020; Volum 11 (44). ISSN 2041-6520.s 12081 - 12088.s doi: 10.1039/d0sc03664a.
    • Schneider, Yannik Karl-Heinz; Jenssen, Marte; Isaksson, Johan; Østnes Hansen, Kine; Andersen, Jeanette Hammer; Hansen, Espen. Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.. Microorganisms 2020; Volum 8 (7). ISSN 2076-2607.s 1 - 17.s doi: 10.3390/microorganisms8071042.
    • Dobrovolska, Olena; Brilkov, Maxim; Madeleine, Noëlly; Ødegaard-Fougner, Øyvind; Strømland, Øyvind; Martin, Stephen R.; De Marco, Valeria; Christodoulou, Evangelos; Teigen, Knut; Isaksson, Johan; Underhaug, Jarl; Reuter, Nathalie; Aalen, Reidunn B.; Aasland, Rein; Halskau, Øyvind. The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection. The FEBS Journal 2020; Volum 287. ISSN 1742-464X.s 4458 - 4480.s doi: 10.1111/febs.15256.
    • Hansen, Ida Kristine Østnes; Isaksson, Johan; Poth, Aaron G.; Østnes Hansen, Kine; Andersen, Aaron John Christian; Richard, Céline Sarah Marine; Blencke, Hans-Matti; Stensvåg, Klara; Craik, David J.; Haug, Tor. Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens. Marine Drugs 2020; Volum 18 (1). ISSN 1660-3397.s doi: 10.3390/md18010051.
    • Moreno, Aitor; Østnes Hansen, Kine; Isaksson, Johan. CSSF-CLIP-HSQMBC: measurement of heteronuclear coupling constants in severely crowded spectral regions. RSC Advances 2019; Volum 9 (62). ISSN 2046-2069.s 36082 - 36087.s doi: 10.1039/c9ra04118d.
    • Østnes Hansen, Kine; Andersen, Jeanette hammer; Bayer, Annette; Pandey, Sunil Kumar; Lorentzen, Marianne; Jørgensen, Kåre Bredeli; Sydnes, Magne Olav; Guttormsen, Yngve; Baumann, Matthias; Koch, Uwe; Klebl, Bert; Eickhoff, Jan; Haug, Bengt Erik; Isaksson, Johan; Hansen, Espen. Kinase chemodiversity from the Arctic: the breitfussins. Journal of Medicinal Chemistry 2019; Volum 62 (22). ISSN 0022-2623.s 10167 - 10181.s doi: 10.1021/acs.jmedchem.9b01006.
    • Schneider, Yannik Karl-Heinz; Østnes Hansen, Kine; Isaksson, Johan; Ullsten-Wahlund, Sara Maria; Hansen, Espen; Andersen, Jeanette Hammer. Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.. Molecules 2019; Volum 24 (21). ISSN 1420-3049.s doi: 10.3390/molecules24213991.
    • Michael Siranjeevi, Raja Priyanka Mary; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer; Østnes Hansen, Kine. Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana. Natural Product Research 2019; Volum 34 (14). ISSN 1478-6419.s 2059 - 2064.s doi: 10.1080/14786419.2019.1574788.
    • Lund, Bjarte Aarmo; Thomassen, Ane Molden; Nesheim, Birgit Helene Berg; Carlsen, Trine Josefine Olsen; Isaksson, Johan; Christopeit, Tony; Leiros, Hanna-Kirsti S.. The biological assembly of OXA‐48 reveals a dimer interface with high charge complementarity and very high affinity. The FEBS Journal 2018; Volum 285 (22). ISSN 1742-464X.s 4214 - 4228.s doi: 10.1111/febs.14643.
    • Østnes Hanssen, Kine; Isaksson, Johan; Glomsaker, Eirin; Andersen, Jeanette hammer; Hansen, Espen. Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan Alcyonidium gelatinosum. Molecules 2018; Volum 23 (6). ISSN 1420-3049.s doi: 10.3390/molecules23061481.
    • Grip, Jostein; Engstad, Rolf Einar; Skjæveland, Ingrid; Skalko-Basnet, Natasa; Isaksson, Johan; Basnet, Purusotam; Holsæter, Ann Mari. Beta-glucan-loaded nanofiber dressing improves wound healing in diabetic mice. European Journal of Pharmaceutical Sciences 2018; Volum 121. ISSN 0928-0987.s 269 - 280.s doi: 10.1016/j.ejps.2018.05.031.
    • Kristoffersen, Venke; Rämä, Teppo; Isaksson, Johan; Andersen, Jeanette hammer; Gerwick, William H.; Hansen, Espen. Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group. Marine Drugs 2018; Volum 16 (5). ISSN 1660-3397.s 1 - 19.s doi: 10.3390/md16050163.
    • Ahkter, Sundus; Lund, Bjarte Aarmo; Ismael, Aya; Langer, Manuel; Isaksson, Johan; Christopeit, Tony; Leiros, Hanna-Kirsti S.; Bayer, Annette. A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design. European Journal of Medicinal Chemistry 2018; Volum 145. ISSN 0223-5234.s 634 - 648.s doi: 10.1016/j.ejmech.2017.12.085.
    • Hansen, Kine Østnes; Isaksson, Johan; Bayer, Annette; Johansen, Jostein a; Andersen, Jeanette hammer; Hansen, Espen. Securamine Derivatives from the Arctic Bryozoan Securiflustra securifrons. Journal of natural products 2017; Volum 80 (12). ISSN 0163-3864.s 3276 - 3283.s doi: 10.1021/acs.jnatprod.7b00703.
    • Michael Siranjeevi, Raja Priyanka Mary; Hanssen, Kine Østnes; Isaksson, Johan; Andersen, Jeanette hammer; Hansen, Espen. A Novel Brominated Alkaloid Securidine A, Isolated from the Marine Bryozoan Securiflustra securifrons. Molecules 2017; Volum 22 (7). ISSN 1420-3049.s doi: 10.3390/molecules22071236.
    • Rothweiler, Ulli; Stensen, Wenche; Brandsdal, Bjørn Olav; Isaksson, Johan; Leeson, Frederick Alan; Engh, Richard Alan; Svendsen, John Sigurd Mjøen. Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules. Journal of Medicinal Chemistry 2016; Volum 59 (21). ISSN 0022-2623.s 9814 - 9824.s doi: 10.1021/acs.jmedchem.6b01086.
    • Olsen, Elisabeth Klungerbo; Hansen, Espen; Moodie, Lindon W.K; Isaksson, Johan; Sepcic, Kristina; Cergolj, Marija; Svenson, Johan; Andersen, Jeanette hammer. Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs. Organic and biomolecular chemistry 2016; Volum 14 (5). ISSN 1477-0520.s 1629 - 1640.s doi: 10.1039/c5ob02416a.
    • Olsen, Elisabeth Klungerbo; Søderholm, Kine; Isaksson, Johan; Andersen, Jeanette hammer; Hansen, Espen. Metabolomic Profiling Reveals the N-Acyl-Taurine Geodiataurine in Extracts from the Marine Sponge Geodia macandrewii (Bowerbank). Journal of natural products 2016; Volum 79 (5). ISSN 0163-3864.s 1285 - 1291.s doi: 10.1021/acs.jnatprod.5b00966.
    • Capar, Jan; Zonneveld, Job; Berg, Steffen; Isaksson, Johan; Gagnon, Kevin J.; Kolle, Ekaney Thomas; Ghosh, Abhik. Demetalation of copper undecaarylcorroles: Molecular structures of a free-base undecaarylisocorrole and a gold undecaarylcorrole. Journal of Inorganic Biochemistry 2016; Volum 162. ISSN 0162-0134.s 146 - 153.s doi: 10.1016/j.jinorgbio.2016.06.026.
    • Stierhof, Marc; Hansen, Kine; Sharma, Mukesh; Feussner, Klaus; Subko, Karolina; Diaz-Rullo, Fernando Fernàndez; Isaksson, Johan; Pèrez-Victoria, Ignacio; Clarke, David; Hansen, Espen; Jaspars, Marcel; Tabudravu, Jioji N.. New cytotoxic callipeltins from the Solomon Island marine sponge Asteropus sp.. Tetrahedron 2016; Volum 72 (44). ISSN 0040-4020.s 6929 - 6934.s doi: 10.1016/j.tet.2016.09.016.
    • Solstad, Runar Gjerp; Li, Chun; Isaksson, Johan; Johansen, Jostein a; Svenson, Johan; Stensvåg, Klara; Haug, Tor. Novel antimicrobial peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the Edible sea urchin Echinus esculentus have 6-br-trp post-translational modifications. PLOS ONE 2016; Volum 11 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0151820.
    • Albert, Anastasia; Eksteen, Jacobus Johannes; Isaksson, Johan; Sengee, Myagmarsuren; Hansen, Terkel; Vasskog, Terje. General approach to determine disulfide connectivity in cysteine-rich peptides by sequential alkylation on solid phase and mass spectrometry. Analytical Chemistry 2016; Volum 88 (19). ISSN 0003-2700.s 9539 - 9546.s doi: 10.1021/acs.analchem.6b02115.
    • Demissie, Taye Beyene; Kostenko, Nataliya; Komorovsky, Stanislav; Repisky, Michal; Isaksson, Johan; Bayer, Annette; Ruud, Kenneth. Experimental and four-component relativistic DFT studies of tungsten carbonyl complexes. Journal of Physical Organic Chemistry 2015; Volum 28 (12). ISSN 0894-3230.s 723 - 731.s doi: 10.1002/poc.3476.
    • Isaksson, Johan; Woestenenk, Esmeralda; Sahlberg, Christer; Agback, Tatiana. Backbone nuclear magnetic resonance assignment of human deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase). Biomolecular NMR Assignments 2014; Volum 8 (1). ISSN 1874-2718.s 81 - 84.s doi: 10.1007/s12104-013-9457-7.
    • Sivertsen, Annfrid; Isaksson, Johan; Leiros, Hanna-Kirsti S.; Svenson, Johan; Svendsen, John Sigurd; Brandsdal, Bjørn Olav. Synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site II of human serum albumin. BMC Structural Biology 2014; Volum 14:4. ISSN 1472-6807.s doi: 10.1186/1472-6807-14-4.
    • Sivertsen, Annfrid; Tørfoss, Veronika; Isaksson, Johan; Ausbacher, Dominik; Anderssen, Trude; Brandsdal, Bjørn Olav; Havelkova, Martina; Skjørholm, Anne Elisabeth; Strøm, Morten B.. Anticancer potency of small linear and cyclic tetrapeptides and pharmacokinetic investigations of peptide binding to human serum albumin. Journal of Peptide Science 2014; Volum 20 (4). ISSN 1075-2617.s 279 - 291.s doi: 10.1002/psc.2615.
    • Naderkhani, Elenaz; Isaksson, Johan; Ryzhakov, Alexey; Flaten, Gøril Eide. Development of a biomimetic phospholipid vesicle-based permeation assay for the estimation of intestinal drug permeability. Journal of Pharmaceutical Sciences 2014; Volum 103 (6). ISSN 0022-3549.s 1882 - 1890.s doi: 10.1002/jps.23954.
    • Li, Xiaojun; Hopmann, Kathrin Helen; Hudecova, Jana; Isaksson, Johan; Novotná, Jana; Stensen, Wenche; Andrushchenko, Valery; Urbanová, Marie; Svendsen, John Sigurd; Bour, Petr; Ruud, Kenneth. Determination of Absolute Configuration and Conformation of a Cyclic Dipeptide by NMR and Chiral Spectroscopic Methods. Journal of Physical Chemistry A 2013; Volum 117 (8). ISSN 1089-5639.s 1721 - 1736.s doi: 10.1021/jp311151h.
    • Demissie, Taye B.; Repisky, Michal; Komorovsky, Stanislav; Isaksson, Johan; Svendsen, John Sigurd; Dodziuk, H; Ruud, Kenneth. Four-component relativistic chemical shift calculations of halogenated organic compounds. Journal of Physical Organic Chemistry 2013; Volum 26 (8). ISSN 0894-3230.s 679 - 687.s doi: 10.1002/poc.3157.
    • Olsen, Elisabeth Klungerbo; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer. Cellular Antioxidant Effect of Four Bromophenols from the Red Algae, Vertebrata lanosa. Marine Drugs 2013; Volum 11. ISSN 1660-3397.s 2769 - 2784.s doi: 10.3390/md11082769.
    • Østnes Hanssen, Kine; Schuler, Bruno; Williams, Antony J.; Demissie, Taye B.; Hansen, Espen; Andersen, Jeanette hammer; Svenson, Johan; Blinov, Kirill; Repisky, Michal; Mohn, Fabian; Meyer, Gerhard; Svendsen, John Sigurd; Ruud, Kenneth; Elyashberg, Mikhail; Gross, Leo; Jaspars, Marcel; Isaksson, Johan. A Combined Atomic Force Microscopy and Computational Approach for the Structural Elucidation of Breitfussin A and B: Highly Modified Halogenated Dipeptides from Thuiaria breitfussi. Angewandte Chemie International Edition 2012; Volum 51 (49). ISSN 1433-7851.s 12238 - 12241.s doi: 10.1002/anie.201203960.
    • Kovacs, H; Agback, T; Isaksson, Johan. Probing water-protein contacts in a MMP-12/CGS27023A complex by nuclear magnetic resonance spectroscopy. Journal of Biomolecular NMR 2012; Volum 53 (2). ISSN 0925-2738.s 85 - 92.s doi: 10.1007/s10858-012-9624-7.
    • Tørfoss, Veronika; Isaksson, Johan; Ausbacher, Dominik; Brandsdal, Bjørn Olav; Flaten, Gøril Eide; Anderssen, Trude; Cavalcanti Jacobsen, Cristiane de Albuquerque; Havelkova, Martina; Nguyen, Leonard T.; Vogel, Hans J.; Strøm, Morten B.. Improved anticancer potency by head-to-tail cyclization of short cationic anticancer peptides containing a lipophilic b2,2-amino acid. Journal of Peptide Science 2012; Volum 18 (10). ISSN 1075-2617.s 609 - 619.s doi: 10.1002/psc.2441.
    • Isaksson, Johan; Brandsdal, Bjørn Olav; Engqvist, Stig Olov Magnus; Flaten, Gøril Eide; Svendsen, John Sigurd; Stensen, Wenche. A Synthetic Antimicrobial Peptidomimetic (LTX 109): Stereochemical Impact on Membrane Disruption. Journal of Medicinal Chemistry 2011; Volum 54 (16). ISSN 0022-2623.s 5786 - 5795.s doi: 10.1021/jm200450h.
    • Isaksson, Johan; Nyström, Susanne; Derbyshire, Dean; Wallberg, Hans; Agback, Tatiana; Kovacs, Helena; Bertini, Ivano; Giachetti, Andrea; Luchinat, Claudio. Does a Fast Nuclear Magnetic Resonance Spectroscopy- and X-Ray Crystallography Hybrid Approach Provide Reliable Structural Information of Ligand-Protein Complexes? A Case Study of Metalloproteinases. Journal of Medicinal Chemistry 2009; Volum 52. ISSN 0022-2623.s 1712 - 1722.s doi: 10.1021/jm801388q.
    • Isaksson, Johan; Chattopadhyaya, Jyoti. A Uniform Mechanism Correlating Dangling-End Stabilization and Stacking Geometry. Biochemistry 2005; Volum 44. ISSN 0006-2960.s 5390 - 5401.s doi: 10.1021/bi047414f.
    • Isaksson, Johan; Plashkevych, Oles; Pradeepkumar, P. I.; Chatterjee, S.; Barman, J.; Pathmasiri, W.; Shrivastava, P.; Petit, Catherine; Chattopadhyaya, Jyoti. Oxetane Locked Thymidine in the Dickerson-Drew Dodecamer Causes Local Base Pairing Distortions - An NMR Structure and Hydration Study. Journal of Biomolecular Structure and Dynamics 2005; Volum 23 (3). ISSN 0739-1102.s 299 - 330.
    • Isaksson, Johan; Acharya, Sandipta; Barman, J.; Cheruku, Pradeep; Chattopadhyaya, Jyoti. Single-Stranded Adenine-Rich DNA and RNA Retain Structural Characteristics of Their Respective Double-Stranded Conformations and Show Directional Differences in Stacking Pattern. Biochemistry 2004; Volum 43. ISSN 0006-2960.s 15996 - 16010.s doi: 10.1021/bi048221v.
    • Acharya, Sandipta; Barman, Jharna; Cheruku, Pradeep; Chatterjee, Subhrangsu; Acharya, Parag; Isaksson, Johan; Chattopadhyaya, Jyoti. Significant pKa Perturbation of Nucleobases Is an Intrinsic Property of the Sequence Context of DNA and RNA. Journal of the American Chemical Society 2004; Volum 126. ISSN 0002-7863.s 8674 - 8681.s doi: 10.1021/ja048484c.
    • Boon, Elizabeth M.; Barton, Jacqueline K.; Pradeepkumar, P. I.; Isaksson, Johan; Petit, Catherine; Chattopadhyaya, Jyoti. An Electrochemical Probe of DNA Stacking in an Antisense Oligonucleotide Containing a C3'-endo-Locked Sugar. Angewandte Chemie International Edition 2002; Volum 41 (8). ISSN 1433-7851.s 3402 - 3405.
    • Isaksson, Johan; Zamaratski, Edouard; Maltseva, Tatiana; Agback, Peter; Kumar, A.; Chattopadhyaya, Jyoti. The First Example of a Hoogsteen Basepaired DNA Duplex in Dynamic Equilibrium with a Watson-Crick Basepaired Duplex - A Structural (NMR), Kinetic and Thermodynamic Study. Journal of Biomolecular Structure and Dynamics 2001; Volum 18 (6). ISSN 0739-1102.s 783 - 806.
    • Zamaratski, Edouard; Trifonova, Anna; Acharya, Parag; Isaksson, Johan; Maltseva, Tatiana; Chattopadhyaya, Jyoti. Do the 16-mer, 5'-GUGGUCUGAUGAGGCC-3' and the 25-mer, 5'-GGCCGAAACUCGUAAGAGUCACCAC-3', Form a Hammerhead Ribozyme Structure in Physiological Conditions? An NMR and UV Thermodynamic Study. Nucleosides, Nucleotides & Nucleic Acids 2001; Volum 20. ISSN 1525-7770.s 1219 - 1223.
    • Isaksson, Johan; Maltseva, Tatiana; Agback, Peter; Luo, X.; Kumar, A; Zamaratski, Edouard; Chattopadhyaya, Jyoti. A Single Carbocyclic Nucleotide Substitution in a 12mer DNA Gives a Hoogsteen Basepaired Duplex (Till 38°C) and a Hairpin (Till 65°C). A 600 MHz NMR Spectroscopic Study. Nucleosides, Nucleotides & Nucleic Acids 1999; Volum 18. ISSN 1525-7770.s 1593 - 1596.
  • Isaksson, Johan. CSSF-CLIP-HSQMBC: Measurement of heteronuclear coupling constants in severely crowded spectral regions. MR 2020 2020-01-07 - 2020-01-08 2020.
  • Moreno, Aitor; Hanssen, Kine Ø.; Isaksson, Johan. CSSF-CLIP-HSQMBC: Measurement of heteronuclear coupling constants in severely crowded spectral regions. SMASH 2019 2019-09-22 - 2019-09-25 2019.
  • Isaksson, Johan. CSSF-CLIP-HSQMBC: Measurement of heteronuclear coupling constants in severely crowded spectral regions. SMASH 2019 2019-09-22 - 2019-09-25 2019.
  • Michael, Priyanka; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer; Østnes Hansen, Kine. Dendrobeaniamine A, a New Alkaloid from the Arctic Marine bryozoan Dendrobeania murrayana. BIOPROSP_19 2019-02-25 - 2019-02-27 2019.
  • Hanssen, Kine Ø.; Andersen, Jeanette hammer; Klebl, Bert; Eickhoff, Jan; Isaksson, Johan; Hansen, Espen. Novel kinase inhibitors from the Arctic marine hydrozoan Thuiaria breitfussi. BIOPROSP_19 2019-02-25 - 2019-02-27 2019.
  • Isaksson, Johan; Sarre, Birta Ravdna. “Dynamics characterization of dUTPase, a new target in cancer therapy”. MR2018 2018-03-07 - 2018-03-09 2018.
  • Haug, Tor; Solstad, Runar Gjerp; Li, Chun; Isaksson, Johan; Johansen, Jostein a; Svenson, Johan; Stensvåg, Klara. Halogenated antimicrobial peptides from the red sea urchin, Echinus esculentus.. The 8th International Conference on Marine Bioprospecting (BIOPROSP 2017) 2017-03-08 - 2017-03-10 2017.
  • Boomgaren, Marc; Sarre, Birta Ravdna; Andberg, Tor Arne Heim; Brandsdal, Bjørn Olav; Isaksson, Johan; Hansen, Jørn H. Synthesis and exploration of a novel molecular scaffold for dUTPase inhibition: Aiming for new anticancer agents. Organisk kjemisk vintermøte 2017 2017-01-12 - 2017-01-15 2017.
  • Pierechod, Marcin Miroslaw; Krzysztof, Tarnowski; Arkadiusz, Ciesielski; Klimecka, Maria; Isaksson, Johan; Poznański, Jarosław; Dobrowolska, Grażyna; Engh, Richard A.. Crystallization of Arabidopsis thaliana SnRK2‐interacting Calcium Sensor, the kinase inhibitor containing EF‐hand motifs. Norwegian Biochemical Society contact meeting 2016-01-21 - 2016-01-23 2016.
  • Olsen, Elisabeth Klungerbo; Søderholm, Kine; Isaksson, Johan; Andersen, Jeanette hammer; Hansen, Espen. Metabolomic Profiling of Two Related Marine Sponges From the Coast of Norway Reveals a New N-acyl Taurine. Gordon Research Conference on Marine Natural Products 2016-03-06 - 2016-03-11 2016.
  • Olsen, Elisabeth Klungerbo; Hansen, Espen; Moodie, Lindon W.K; Isaksson, Johan; Sepcic, Kristina; Cergolj, Marija; Svenson, Johan; Andersen, Jeanette hammer. ChemInform Abstract: Marine AChE Inhibitors Isolated from Geodia barretti: Natural Compounds and Their Synthetic Analogues. ChemInform 2016; Volum 47 (24). ISSN 0931-7597.s doi: 10.1002/chin.201624208.
  • Lund, Bjarte Aarmo; Christopeit, Tony; Ahkter, Sundus; Guttormsen, Yngve; Isaksson, Johan; Bayer, Annette; Leiros, Hanna-Kirsti S.. Structure-Guided Drug Design for the Antibiotic Resistance Enzyme OXA-48. ASM Microbe 2016 2016-06-16 - 2016-06-20 2016.
  • Sarre, Birta Ravdna; Lundström, Patrik; Boomgaren, Marc; Woestenenk, Esmeralda; Hansen, Jørn H; Agback, Tatiana; Isaksson, Johan. Characterization of human dUTPase, a new target in cancer therapy. MR 2016 2016-06-15 - 2016-06-17 2016.
  • Isaksson, Johan. Pharmacophore mapping of DYRK1A with X-ray and NMR. MR 2016 2016-06-15 - 2016-06-17 2016.
  • Lund, Bjarte Aarmo; Akhter, Sundus; Guttormsen, Yngve; Christopeit, Tony; Isaksson, Johan; Bayer, Annette; Leiros, Hanna-Kirsti S.. Structure-guided drug design for the antibiotic resistance enzyme OXA-48. 7th Annual BioStruct Conference 2016-08-25 - 2016-08-28 2016.
  • Solstad, Runar Gjerp; Li, Chun; Isaksson, Johan; Johansen, Jostein a; Svenson, Johan; Stensvåg, Klara; Haug, Tor. Novel antimicrobial peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the edible sea urchin Echinus esculentus have 6-Br-Trp post-translational modifications. 6th International Meeting on Antimicrobial Peptides 2016-08-31 - 2016-09-03 2016.
  • Isaksson, Johan. Structure elucidation of breitfussins A-B. MR 2014 2014-01-13 - 2014-01-15 2014.
  • Hanssen, Kine Ø.; Schuler, Bruno; Williams, Antony J.; Demissie, Taye B.; Hansen, Espen; Andersen, Jeanette hammer; Svenson, Johan; Svendsen, John Sigurd; Gross, Leo; Jaspars, Marcel; Isaksson, Johan. Introducing Atomic Force Microscopy in Structure Elucidation. SMASH 2013 2013-09-22 - 2013-09-25 2013.
  • Isaksson, Johan. NMR studies of small antimicrobial peptides. MR 2012 2012-01-09 - 2012-01-11 2012.
  • Olsen, Elisabeth; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer. Antioxidant effect of four bromophenols from the red algae Vertebrata lanosa. Planta Medica 2012; Volum 78 (11). ISSN 0032-0943.s 1146 - 1146.
  • Olsen, Elisabeth Klungerbo; Hansen, Espen; Isaksson, Johan; Andersen, Jeanette hammer. Antioxidant effect of four bromophenols from the red algae Vertebrata lanosa. International Congress on Natural Products Research 2012-07-28 - 2012-08-01 2012.
  • Isaksen, Geir Villy; Isaksson, Johan; Svendsen, John Sigurd; Brandsdal, Bjørn Olav. Structural studies of small cationic antimicrobial peptides by NMR and computer simulations have facilitated a refined pharmacophore model able to predict activity versus Staphylococcus aureus. SMASH 2011 2011-09-18 - 2011-09-21 2011.
  • Agback, Tatiana; Woestenenk, Esmeralda; Sahlberg, Christer; Isaksson, Johan; Kovacs, Helena. Selective labeling in large proteins as a tool for monitoring ligand-protein contacts by NMR. Part I: Proof of concept demonstrated on dUTPase complexes. SMASH 2010 2010-09-26 - 2010-09-29 2010.
  • Isaksen, Geir Villy; Karstad, Rasmus Tørnes; Isaksson, Johan Mattias; Svenson, Johan; Svendsen, John Sigurd; Brandsdal, Bjørn Olav. Structure of short cationic antimicrobial peptides and their interactions with membranes as revealed by MD simulations. ISB Winter School 2010 2010-12-07 - 2010-12-10 2010.
  • Isaksson, Johan; Flaten, Gøril Eide; Brandsdal, Bjørn Olav; Svendsen, John Sigurd. Studies of Small Synthetic Anti-microbial Peptides by NMR and Molecular Modeling. Joint EUROMAR 2010 + ISMAR 2010 2010-07-05 - 2010-07-09 2010.
  • Kovacs, Helena; Isaksson, Johan; Nyström, Susanne; Agback, Tatiana; Bertini, Ivano; Luchinat, Claudio. Determination of Water-Protein contacts by NMR. Application to the MMP-CGS27023A complex. SMASH 2008 2008-09-07 - 2010-09-10 2008.
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    Undervisning

    Teaching in the NMR course, KJE-3303/8303.


    Member of research group



    REALF C 206.2

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