Bilde av Einvik, Christer
Photo: Christian Halvorsen
Bilde av Einvik, Christer
Professor Klinihkalaš medisiinna instituhtta christer.einvik@uit.no +4777620886 + 47 41548510

Christer Einvik



  • Swapnil Bhavsar, Lotte Olsen, Cecilie Løkke, Jan Koster, Trond Flægstad, Christer Einvik :
    Hsa-miR-323a-3p functions as a tumor suppressor and targets STAT3 in neuroblastoma cells
    Frontiers in pediatrics 2023 ARKIV / DOI
  • Peter Utnes, Cecilie Løkke, Trond Flægstad, Christer Einvik :
    Clinically Relevant Biomarker Discovery in High-Risk Recurrent Neuroblastoma
    Cancer Informatics 2019 ARKIV / DOI
  • Roth Sarah Andrea, Øyvind Holsbø Hald, Steffen Fuchs, Cecilie Løkke, Ingvild Mikkola, Trond Flægstad et al.:
    MicroRNA-193b-3p represses neuroblastoma cell growth via downregulation of Cyclin D1, MCL-1 and MYCN
    OncoTarget 2018 ARKIV / DOI
  • Swapnil Parashram Bhavsar, Cecilie Løkke, Trond Flægstad, Christer Einvik :
    Hsa-miR-376c-3p targets cyclin D1 and induces G1-cell cycle arrest in neuroblastoma cells
    Oncology Letters 2018 ARKIV / DOI
  • Øyvind Holsbø Hald, Lotte Olsen, Gabriel Gallo-Oller, Lotta Helena Maria Elfman, Cecilie Løkke, Per Kogner et al.:
    Inhibitors of ribosome biogenesis repress the growth of MYCN-amplified neuroblastoma.
    Oncogene 2018 ARKIV / DOI
  • Sarah A Roth, Erik Knutsen, Tonje Fiskaa, Peter Andree Utnes, Swapnil Parashram Bhavsar, Øyvind Hald et al.:
    Next generation sequencing of microRNAs from isogenic neuroblastoma cell lines isolated before and after treatment
    Cancer Letters 2016 DOI
  • Malin Wickström, Cecilia Dyberg, Jelena Milosevic, Christer Einvik, Raul Calero, Baldur Sveinbjørnsson et al.:
    Wnt/β-catenin pathway regulates MGMT gene expression in cancer and inhibition of Wnt signalling prevents chemoresistance
    Nature Communications 2015 ARKIV / DOI
  • Bjørn Helge Haug, Øyvind Hald, Peter Utnes, Sarah A Roth, Cecilie Løkke, Trond Flægstad et al.:
    Exosome-like extracellular vesicles from MYCN-amplified neuroblastoma cells contain oncogenic miRNAs
    Anticancer Research 2015 SAMMENDRAG / ARKIV
  • Hanna Zirath, Anna Frenzel, Ganna Oliynyk, Lova Segerstrom, Ulrica K. Westermark, Karin Larsson et al.:
    MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
    Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2013 DOI
  • Jochen Buechner, Christer Einvik :
    N-myc and Noncoding RNAs in Neuroblastoma
    Molecular Cancer Research 2012 DOI
  • Jørn Remi Henriksen, Bjørn Helge Haug, Jochen Büchner, Ellen Tømte, Cecilie Løkke, Trond Flaegstad et al.:
    Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma
    BMC Developmental Biology 2011 FULLTEKST / ARKIV / DOI
  • Jochen Buechner, Ellen Tømte, Bjørn Helge Haug, Jørn Remi Henriksen, Cecilie Løkke, Trond Flægstad et al.:
    Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
    British Journal of Cancer 2011 ARKIV / DOI
  • Bjørn Helge Haug, Jørn Remi Henriksen, Jochen Buechner, Dirk Geerts, Ellen Tømte, Per Kogner et al.:
    MYCN-regulated miRNA-92 inhibits secretion of the tumor suppressor DICKKOPF-3 (DKK3) in neuroblastoma
    Carcinogenesis 2011 DOI
  • Jørn Remi Henriksen, Jochen Büchner, Cecilie Løkke, Trond Flaegstad, Christer Einvik :
    Inhibition of Gene Function in Mammalian Cells Using Short-Hairpin RNA (shRNA)
    Humana Press 2011 DOI
  • Jochen Büchner, Jørn Remi Henriksen, Bjørn Helge Haug, Ellen Tømte, Trond Flaegstad, Christer Einvik :
    Inhibition of mir-21, which is up-regulated during MYCN knockdown-mediated differentiation, does not prevent differentiation of neuroblastoma cells
    Differentiation 2011 DOI
  • Henrik Nielsen, christer Einvik, Thomas E Lentz, MM Hedegaard, Steinar Johansen :
    A conformational switch in the DiGIR1 ribozyme involved in release and folding of the downstream I-DirI mRNA
    RNA: A publication of the RNA Society 2009 DOI
  • B Beckert, Henrik Nielsen, christer Einvik, Steinar Johansen, E Westhof, B Masquida :
    Molecular modelling of the GIR1 branching ribozyme gives new insight into evolution of structurally related ribozymes
    EMBO Journal 2008 DOI
  • Jørn Remi Henriksen, cecilie LØkke, Martin Hammerø, Dirk Geerts, R Versteeg, Trond Flaegstad et al.:
    Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines
    Nucleic Acids Research (NAR) 2007 DOI
  • Tonje Fiskaa, Eirik Wasmuth Lundblad, Jørn Remi Henriksen, Steinar Johansen, Christer Einvik :
    RNA reprogramming of alpha-mannosidase mRNA sequences in vitro by myxomycete group IC1 and IE ribozymes
    The FEBS Journal 2006
  • Odd Gunnar Wikmark, Christer Einvik, JF De Jonckheere, Steinar Johansen :
    Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron
    BMC Evolutionary Biology 2006
  • Odd Gunnar Wikmark, Christer Einvik, Johan F De Jonckheere, Steinar Daae Johansen :
    Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron
    BMC Ecology and Evolution 2006 DOI
  • Eirik Wasmuth Lundblad, Christer Einvik, S Rønning, Kari B. Haugli, Steinar Johansen :
    Twelve group I Introns in the same pre-rRNA transcript of the myxomycete Fuligo septica: RNA processing and evolution
    Molecular Biology and Evolution (MBE) 2004
  • Christer Einvik, Tonje Fiskaa, Eirik Wasmuth Lundblad, Steinar Johansen :
    Optimization and application of the group I ribozyme trans-splicing reaction
    Methods in molecular biology 2004
  • Henrik Nielsen, Tonje Fiskaa, Åsa Birna Birgisdottir, Peik Haugen, christer Einvik, Steinar Johansen :
    The ability to form full-length intron RNA circles is a general property of nuclear group I introns
    RNA: A publication of the RNA Society 2003
  • Steinar Johansen, christer Einvik, Henrik Nielsen :
    DiGIR1 and NaGIR1: naturally occurring group I-like ribozymes with unique core organization and evolved biological role
    Biochimie 2002
  • Steinar Daae Johansen, morten Andreassen, Åsa birna Birgisdottir, Dag-Hugo Coucheron, Christer Einvik, Tonje Fiskaa et al.:
    Group I introns are very common in nuclear SSU rDNA and LSU rDNA of Myxomycetes
    Scripta Botanica Belgica 2002
  • christer Einvik, Henrik Nielsen, R Nour, Steinar Johansen :
    Flanking sequences with essential role in hydrolysis of a self-cleaving group I-like ribozyme
    Nucleic Acids Research (NAR) 2000
  • Yusuke Suenaga, Christer Einvik, Atsushi Takatori, Yuyan Zhu :
    Editorial: Molecular Mechanisms and Treatment of MYCN-Driven Tumors
    Frontiers in Oncology 2021 DOI
  • Trond Flægstad, Bjørn Helge Haug, Jochen Buechner, Jørn Remi Henriksen, Per Kogner, Tommy Martinson et al.:
    MYCN-REGULATED MIRNA-92 INHIBITS SECRETION OF THE TUMOR SUPPRESSOR DICKKOPF-3 (DKK3) IN NEUROBLASTOMA
    Pediatric Blood & Cancer 2011
  • Trond Flaegstad, christer Einvik, Jørn Remi Henriksen :
    Targeted MYCN suppression and its effect on miRNA in neuroblastoma
    UiT Norges arktiske universitet 2010 FULLTEKST
  • Jørn Remi Henriksen, Bjørn Helge Haug, Jochen Büchner, cecilie LØkke, Trond Flaegstad, christer Einvik :
    Conditional MYCN knockdown using shRNAs encoded by retrovirus vectors
    2010
  • Bjørn Helge Haug, Jørn Remi Henriksen, Baldur Sveinbjørnsson, Trond Flaegstad, christer Einvik :
    The tumour suppressor DKK3 is a direct target of MYCN regulated miRNAs
    2010
  • Jørn Remi Henriksen, Jochen Büchner, Bjørn Helge Haug, christer Einvik, Trond Flaegstad :
    Combination of RA Treatment and MYCN-knockdown in MYCN Amplified Neuroblastoma
    2010
  • Trond Flaegstad, Jochen Büchner, Jørn Remi Henriksen, cecilie LØkke, Ellen Tømte, Bjørn Helge Haug et al.:
    MYCN PARTICIPATES IN A REGULATORY MIRNA NETWORK IN MYCN-AMPLIFIED NEUROBLASTOMA
    Pediatric Blood & Cancer 2009
  • Jochen Büchner, Jørn Remi Henriksen, cecilie LØkke, Trond Flaegstad, christer Einvik :
    Effect of MYCN downregulation on microRNA expression in neuroblastoma
    2008
  • Jochen Büchner, Jørn Remi Henriksen, cecilie LØkke, Trond Flaegstad, christer Einvik :
    MicroRNA-101 as a potential regulator of MCYN expression in neuroblastoma
    2008

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