Pia Abel zur Wiesch
S.V. Leavitt,
C.A. Rodriguez,
T.C. Bouton,
C.R. Horsburgh,
Pia Karoline Schulz zur Wiesch Schulz zur Wiesch,
B.E. Nichols
et al.:
Outcomes for people with TB by disease severity at presentation
The International Journal of Tuberculosis and Lung Disease 2024 DOI
Antal Martinecz,
Martin J. Boeree,
Andreas H. Diacon,
Rodney Dawson,
Colin Hemez,
Rob Arnoutse
et al.:
High rifampicin peak plasma concentrations accelerate the slow phase of bacterial decline in tuberculosis patients: Evidence for heteroresistance
C.A. Rodriguez,
S.V. Leavitt,
T.C. Bouton,
C.R. Horsburgh,
Pia Abel zur Wiesch,
B. Nichols
et al.:
Survival of people with untreated TB: effects of time, geography and setting
The International Journal of Tuberculosis and Lung Disease 2023 DOI
Jingyi Liang,
Vi Ngoc-Nha Tran,
Colin Hemez,
Pia Abel zur Wiesch
:
Current Approaches of Building Mechanistic Pharmacodynamic Drug-Target Binding Models
Springer 2022 DOI
Vi Ngoc-Nha Tran,
Alireza Shams,
Sinan Ascioglu,
Antal Martinecz,
Jingyi Liang,
Fabrizio Clarelli
et al.:
vCOMBAT: a novel tool to create and visualize a computational model of bacterial antibiotic target-binding
Colin Hemez,
Fabrizio Clarelli,
Adam C. Palmer,
Christina Bleis,
Sören Abel,
Leonid Chindelevitch
et al.:
Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations
Irina Kontsevaya,
Christoph Lange,
Patricia Comella-Del-barrio,
Cristian Coarfa,
Andrew R. Dinardo,
Stephen H. Gillespie
et al.:
Perspectives for systems biology in the management of tuberculosis
Aaron Nicholas Gillman,
Anel Mahmutovic,
Pia Abel zur Wiesch,
Sören Abel
:
The Infectious Dose Shapes Vibrio Cholerae Within-Host Dynamics
Viacheslav N. Kachalov,
Huyen Nguyen,
Suraj Balakrishna,
Luisa Salazar-Vizcaya,
Rami Sommerstein,
Stefan P. Kuster
et al.:
Identifying the drivers of multidrug-resistant Klebsiella pneumoniae at a European level
Fabrizio Clarelli,
Adam Palmer,
Bhupender Singh,
Merete Storflor,
Silje Lauksund,
Ted Cohen
et al.:
Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones
Helen Stagg,
Mary Flook,
Antal Martinecz,
Karina Kielmann,
Pia Abel zur Wiesch,
Aaron Karat
et al.:
All non-adherence is equal, but is some more equal than others? TB in the digital era.
European Respiratory Journal Open Research (ERJ Open Research) 2020 ARKIV
Anel Mahmutovic,
Pia Abel zur Wiesch,
Sören Abel
:
Selection or drift: the population biology underlying transposon insertion sequencing experiments.
Helen R. Stagg,
Mary Flook,
Antal Martinecz,
Karina Kielmann,
Pia Abel zur Wiesch,
Aaron S. Karat
et al.:
All nonadherence is equal but is some more equal than others? Tuberculosis in the digital era
European Respiratory Journal Open Research (ERJ Open Research) 2020 DOI
Antal Martinecz,
Fabrizio Clarelli,
Sören Abel,
Pia Abel zur Wiesch
:
Reaction Kinetic Models of Antibiotic Heteroresistance
Fabrizio Clarelli,
Jingyi Liang,
Antal Martinecz,
Ines Heiland,
Pia Abel zur Wiesch
:
Multi-scale modeling of drug binding kinetics to predict drug efficacy
Burcu Tepekule,
Pia Abel zur Wiesch,
Roger D. Kouyos,
Sebastian Bonhoeffer
:
Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiota
Alyson R. Warr,
Troy P. Hubbard,
Diana Munera,
Carlos J. Blondel,
Pia Abel zur Wiesch,
Sören Abel
et al.:
Transposon-insertion sequencing screens unveil requirements for EHEC growth and intestinal colonization
Antal Martinecz,
Pia Abel zur Wiesch
:
Estimating treatment prolongation for persistent infections
Ting Zhang,
Sören Abel,
Pia Abel zur Wiesch,
Jumpei Sasabe,
Brigid M. Davis,
Darren E. Higgins
et al.:
Deciphering the landscape of host barriers to Listeria monocytogenes infection
Pia Abel zur Wiesch,
Fabrizio Clarelli,
Ted Cohen
:
Using chemical reaction kinetics to predict optimal antibiotic treatment strategies
Amber Kunkel,
Pia Abel zur Wiesch,
Ruvandhi R. Nathavitharana,
Florian M. Marx,
Helen E. Jenkins,
Ted Cohen
:
Smear positivity in paediatric and adult tuberculosis: systematic review and meta-analysis
BMC Infectious Diseases 2016 DOI
Troy Hubbard,
Michael C Chao,
Sören Abel,
Carlos J Blondel,
Pia Abel zur Wiesch,
Xiaohui Zhou
et al.:
Genetic analysis of vibrio parahaemolyticus intestinal colonization
Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2016 DOI
Dominique Cadosch,
Pia Abel zur Wiesch,
Roger Kouyos,
Sebastian Bonhoeffer
:
The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB
Sören Abel,
Pia Karoline Abel-Zur Wiesch Genannt Hülsho,
Hsiao-Han Chang,
Brigid M. Davis,
Marc Lipstich,
Matthew K. Waldor
:
Sequence tag-based analysis of microbial population dynamics
Nature Methods 2015 DOI
Sören Abel,
Pia Schulz Zur Wiesch,
Brigid M. Davis,
Matthew K. Waldor
:
Analysis of Bottlenecks in Experimental Models of Infection
Pia Abel zur Wiesch,
Sören Abel,
Spyridon Gkotzis,
Paolo Ocampo,
Jan Engelstädter,
Trevor Hinkley
et al.:
Classic reaction kinetics can explain complex patterns of antibiotic action
Science Translational Medicine 2015 DOI
Pia Karoline Abel-Zur Wiesch Genannt Hülsho,
Roger D. Kouyos,
Sören Abel,
Wolfgang Viechtbauer,
Sebastian Bonhoeffer
:
Cycling empirical antibiotic therapy in hospitals: meta-analysis and models
PLoS Pathogens 2014 DOI
Sören Abel,
Tabitha Bucher,
Micael Nicollier,
Isabelle Hug,
Volkhard Kaever,
Pia Karoline Abel-Zur Wiesch Genannt Hülsho
et al.:
Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle
PLoS Genetics 2013 DOI
Niklas Koehler,
Sönke Andres,
Matthias Merker,
Viola Dreyer,
Agnieszka John,
Martin Kuhns
et al.:
Pretomanid-resistant tuberculosis
Journal of Infection 2023 DOI
Anel Mahmutovic,
Aaron Nicholas Gillman,
Silje Lauksund,
Natasha-Anne Robson Moe,
Aimé Manzi,
Merete Storflor
et al.:
RESTAMP – Rate estimates by sequence-tag analysis of microbial populations
Vi Ngoc-Nha Tran,
Alireza Shams,
Sinan Ascioglu,
Antal Martinecz,
Jingyi Liang,
Fabrizio Clarelli
et al.:
vCOMBAT: a novel tool to create and visualize a computational model of bacterial antibiotic target-binding
2020 FULLTEKST
Pia Abel zur Wiesch,
Antal Martinecz
:
Mathematical Models of Optimal Antibiotic Treatment
UiT Norges arktiske universitet 2020
Antal Martinecz,
Martin J. Boeree,
Andreas H. Diacon,
Rodney Dawson,
Rob E. Aarnoutse,
Pia Abel zur Wiesch
:
High peak drug concentrations increase the bactericidal action in the slow phase of bacterial elimination in EBA trials of tuberculosis patients. Conference presentation at "2nd Arctic Meeting on Clinical Tuberculosis"
2019
Antal Martinecz,
Martin J. Boeree,
Andreas H. Diacon,
Rodney Dawson,
Rob E. Aarnoutse,
Pia Abel zur Wiesch
:
High peak rifampicin plasma concentrations accelerate the slow phase of bacterial elimination in tuberculosis patients
2019
Pia Abel zur Wiesch
:
How to design dosing strategies
2019
Pia Abel zur Wiesch
:
How to design antibiotic dosing strategies in tuberculosis
2019
Pia Abel zur Wiesch,
Natasha-Anne Robson Moe,
Silje Lauksund,
Antal Martinecz
:
Bacterial replication and death rates during exposure to bactericidal antibiotics
UiT Norges arktiske universitet 2019
Pia Abel zur Wiesch
:
How to design antibiotic dosing strategies
2019
Fabrizio Clarelli,
Bhupender Singh,
Adam Palmer,
Sören Abel,
Ted Cohen,
Pia Abel zur Wiesch
:
Quantitatively predicting antibiotic susceptibility from
biochemical parameters: implications for antibiotic
development and preventing resistance
2018
Antal Martinecz,
Pia Abel zur Wiesch,
Roland R. Regoes
:
Within Host Infection Dynamics: Persisters can infect new sites and cause relapse if the immune clearance is low
2018
Fabrizio Clarelli,
Ted Cohen,
Sören Abel,
Bhupender Singh,
Adam Palmer,
Leonid Chindelevitch
et al.:
How molecular mechanisms of resistance affect resistance evolution
2018
Fabrizio Clarelli,
Bhupender Singh,
Ted Cohen,
Adam Palmer,
Leonid Chindelevitch,
Sören Abel
et al.:
Using models to understand how molecular mechanisms of resistance affect the risk of acquired drug resistance during treatment
2018
Antal Martinecz,
Martin J. Boeree,
Andreas H. Diacon,
Rodney Dawson,
Rob E. Aarnoutse,
Pia Abel zur Wiesch
:
High peak drug concentrations increase the bactericidal action in the
slow phase of bacterial elimination in EBA trials of tuberculosis
patients. Conference presentation at "International Workshop on Clinical Pharmacology of Tuberculosis Drugs 2018" The Hague, Netherlands
2018
Pia Abel zur Wiesch
:
How to design dosing strategies
2018
Antal Martinecz,
Pia Abel zur Wiesch,
Roland Regoes
:
Persistence lengthens the treatment of chronic infections
2018
Antal Martinecz,
Martin J. Boeree,
Andreas H. Diacon,
Rodney Dawson,
Rob E. Aarnoutse,
Pia Abel zur Wiesch
:
High peak drug concentrations increase the bactericidal action in the slow phase of bacterial elimination in EBA trials of tuberculosis patients
2018
Pia Abel zur Wiesch
:
At the interface of chemical kinetics and population biology: how to design antibiotic dosing strategies in tuberculosis
2018
Fabrizio Clarelli,
Leonid Chindelevitch,
Bhupender Singh,
Ted Cohen,
Sören Abel,
Pia Abel zur Wiesch
:
Using models to understand how molecular mechanisms of resistance affect the risk of acquired drug resistance during treatment
2017
Pia Abel zur Wiesch,
Ted Cohen,
Rafał Mostowy,
Alireza Shams
:
Predicting Antibiotic Pharmacodynamics Using Chemical Kinetics
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