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Bilde av Skagseth, Susann
Photo: UiT
Bilde av Skagseth, Susann
Kemiija instituhtta susann.skagseth@uit.no +4777646280 Tromsø

Susann Skagseth

  • Florian van der Ent, Susann Skagseth, Bjarte Aarmo Lund, Jaka Sočan, Julia J. Griese, Bjørn Olav Brandsdal et al.:
    Computational design of the temperature optimum of an enzyme reaction
    Science Advances 2023 ARKIV / DOI
  • Katarzyna Palica, Fritz Deufel, Susann Skagseth, Gabriela Paula Di Santo Metzler, Johannes Thoma, Anna Andersson Rasmussen et al.:
    α-Aminophosphonate inhibitors of metallo-β-lactamases NDM-1 and VIM-2
    RSC Medicinal Chemistry 2023 DOI
  • Katarzyna Palica, Manuela Vorácová, Susann Skagseth, Anna Andersson Rasmussen, Lisa Allander, Madlen Hubert et al.:
    Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters
    ACS Omega 2021 ARKIV / FULLTEKST / DOI
  • Ørjan Samuelsen, Ove Alexander Høgmoen Åstrand, Christopher Frøhlich, Adam Heikal, Susann Skagseth, Trine Josefine Olsen Carlsen et al.:
    ZN148 Is a Modular Synthetic Metallo-beta-Lactamase Inhibitor That Reverses Carbapenem Resistance in Gram-Negative Pathogens In Vivo
    Antimicrobial Agents and Chemotherapy 2020 ARKIV / DATA / DOI
  • Zeeshan Muhammad, Susann Skagseth, Marc Boomgaren, Sundus Akhter, Christopher Frøhlich, Aya Ismael et al.:
    Structural studies of triazole inhibitors with promising inhibitor effects against antibiotic resistance metallo-β-lactamases
    Bioorganic & Medicinal Chemistry 01. Aug 2020 ARKIV / DOI
  • Susann Skagseth, Sundus Akhter, Marianne H. Paulsen, Muhammad Zeeshan, Silje Lauksund, Ørjan Samuelsen et al.:
    Metallo-β-lactamase inhibitors by bioisosteric replacement: preparation, activity and binding
    European Journal of Medicinal Chemistry 2017 ARKIV / DOI
  • Susann Skagseth, Tony Christopeit, Sundus Akhter, Annette Bayer, Ørjan Samuelsen, Hanna-Kirsti S. Leiros :
    Structural insights into TMB-1 and the role of residues 119 and 228 in substrate and inhibitor binding
    Antimicrobial Agents and Chemotherapy 2017 ARKIV / DOI
  • Susann Skagseth, Trine Josefine Olsen Carlsen, Gro Elin Kjæreng Bjerga, James Spencer, Ørjan Samuelsen, Hanna-Kirsti S. Leiros :
    Role of residues W228 and Y233 in the structure and activity of metallo-β-lactamase GIM-1
    Antimicrobial Agents and Chemotherapy 2016 ARKIV / DOI
  • Hanna-Kirsti S. Leiros, Susann Skagseth, Kine Susann Waade Edvardsen, Marit Sjo Lorentzen, Gro Elin Kjæreng Bjerga, Ingar Leiros et al.:
    His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7
    Antimicrobial Agents and Chemotherapy 2014 DOI
  • Vibeke Os, Susann Skagseth, Hanna-Kirsti S. Leiros :
    "Superbugs" skal ikke lengre få herje i fred, Vil gjenreise effekten av antibiotika.
    30. Mar 2017 FULLTEKST
  • Susann Skagseth, Hanna-Kirsti S. Leiros :
    Forskere vil gjenreise effekten av antibiotika. https://forskning.no/kortnytt/forskere-vil-gjenreise-effekten-av-antibiotika
    31. Mar 2017 DATA
  • Susann Skagseth :
    The impact of residue 119 and 228 in the Tripoli metallo-β-lactamase TMB-1 involved in resistance to β-lactam antibiotics" Biostruct conference
    2016
  • Susann Skagseth, Ørjan Samuelsen, Hanna-Kirsti S. Leiros :
    The impact of residues 119 and 228 in the Tripoli metallo-beta-lactamase TMB-1 involved in resistance to beta-lactam antibiotics
    2016
  • Tony Christopeit, Trine Josefine Olsen Carlsen, Anastasia Albert, Susann Skagseth, Hanna-Kirsti S. Leiros :
    Discovery of a Novel Covalent Inhibitor of the Metallo-beta-lactamase NDM-1
    2016
  • Susann Skagseth, Trine Josefine Olsen Carlsen, Sundus Akhter, Muhammad Zeeshan, Ove Alexander Høgmoen Åstrand, Annette Bayer et al.:
    The fight against metallo-beta-lactamases and antibiotic resistance
    2015
  • Tony Christopeit, Trine Josefine Olsen Carlsen, Susann Skagseth, Bjarte Aarmo Lund, Ørjan Samuelsen, Hanna-Kirsti S. Leiros :
    Using fragment screening to identify novel starting points for potent inhibitors of metallo-beta-lactamase VIM-2
    2015
  • Tony Christopeit, Bjarte Aarmo Lund, Trine Josefine Olsen Carlsen, Susann Skagseth, Ørjan Samuelsen, Hanna-Kirsti S. Leiros :
    Using Fragment Screening to Identify Novel Starting Points for Potent Carbapenemase Inhibitors
    2015
  • Susann Skagseth, Trine Josefine Olsen Carlsen, Sundus Akhter, Muhammad Zeeshan, Ove Alexander Høgmoen Åstrand, Annette Bayer et al.:
    The fight against metallo-beta-lactamases and antibiotic resistance
    2015
  • Susann Skagseth, Trine Josefine Olsen Carlsen, Tony Christopeit, Sundus Akhter, Muhammad Zeeshan, Ove Alexander Høgmoen Åstrand et al.:
    The fight against metallo-beta-lactamases and antibiotic resistance
    2015
  • Susann Skagseth, Trine Josefine Olsen Carlsen, Gro Elin Kjæreng Bjerga, Annette Bayer, Ørjan Samulesen, Hanna-Kirsti S. Leiros :
    The importance of residue W228 and Y233 in the metallo-beta-lactamase GIM-1
    2014
  • Marianne H. Paulsen, Stig Olov Magnus Engqvist, Ørjan Samuelsen, Hanna-Kirsti S. Leiros, Susann Skagseth, Kinga Leszczak et al.:
    Synthesis of potential metallo-beta-lactamase inhibitors
    2014
  • Susann Skagseth, Trine Josefine Olsen Carlsen, Gro Elin Kjæreng Bjerga, Annette Bayer, Ørjan Samuelsen, Hanna-Kirsti S. Leiros :
    The importance of residue Trp228 and Tyr233 in the metallo-beta-lactamase GIM-1
    2014
  • Tony Christopeit, Trine Josefine Olsen Carlsen, Susann Skagseth, Bjarte Aarmo Lund, Ørjan Samuelsen, Hanna-Kirsti S. Leiros :
    Characterization of substrate and inhibitor binding to different beta-lactamases using Surface Plasmon Resonance based biosensors
    2014
  • Susann Skagseth, Kine Susann Waade Edvardsen, Gro Elin Kjæreng Bjerga, marit sjo Lorentzen, Ingar Leiros, Ørjan Samulesen et al.:
    Site-directed mutagenesis of metallo-beta-lactamase VIM-7 from the opportunistic human pathogenic bacteria Pseudomonas aeruginosa
    2013

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