Helena Borland Madsen,
J-H Park,
Y Hou,
Z Li,
Lene J. Rasmussen,
D. L. Croteau
et al.:
The cGAS-STING signaling pathway is modulated by urolithin A
Mechanisms of Ageing and Development 2024
DOI
Helena Borland Madsen,
Louise I. Pease,
Rebekah-Louise Scanlan,
Mansour Akbari,
Lene J. Rasmussen,
Daryl P. Shanley
et al.:
The DNA repair enzyme, aprataxin, plays a role in innate immune signaling
Frontiers in Aging Neuroscience 2023
DOI
Mansour Akbari,
Hilde Nilsen,
Nicola Pietro Montaldo
:
Dynamic features of human mitochondrial DNA maintenance and transcription
Frontiers in Cell and Developmental Biology 2022
ARKIV /
DOI
Mansour Akbari,
Shanley Daryl P,
Vilhelm A. Bohr,
Lene Juel Rasmussen
:
Cytosolic Self-DNA-A Potential Source of Chronic Inflammation in Aging
Konstantinos Palikaras,
Kavya Achanta,
Seoyun Choi,
Mansour Akbari,
Vilhelm A. Bohr
:
Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy
Tanima SenGupta,
Konstantinos Palikaras,
Qin Ying Esbensen,
Georgios Konstantinidis,
Francisco Jose Naranjo Galindo,
Kavya Achanta
et al.:
Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology
Mansour Akbari,
Jin Zheng,
Claire Schirmer,
Marie-Line Reynaert,
Anne Loyens,
Bruno Lefebvre
et al.:
Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy
Acta neuropathologica communications 2020
DOI
Shunlei Duan,
Xuerui Han,
Mansour Akbari,
Deborah L Croteau,
Lene Juel Rasmussen,
Vilhelm A. Bohr
:
Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase
Nucleic Acids Research (NAR) 2020
DOI
Evandro Fei Fang,
Yujun Hou,
Konstantinos Palikaras,
Bryan A. Adriaanse,
Jesse S. Kerr,
Beimeng Yang
et al.:
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
Scott Maynard,
Guido Keijzers,
Mansour Akbari,
Michael Ben Ezra,
Arnaldur Hall,
Marya Morevati
et al.:
Lamin A/C promotes DNA base excision repair
Nucleic Acids Research (NAR) 2019
DOI
Mansour Akbari,
Thomas B.L. Kirkwood,
Vilhelm A Bohr
:
Mitochondria in the signaling pathways that control longevity and health span
Ageing Research Reviews 2019
DOI
Jin Zheng,
Deborah L. Croteau,
Vilhelm A Bohr,
Mansour Akbari
:
Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells
Nucleic Acids Research (NAR) 2019
DOI
Yujun Hou,
Hyundong Song,
DL Croteau,
Mansour Akbari,
Vilhelm A. Bohr
:
Genome instability in Alzheimer disease
Mechanisms of Ageing and Development 2017
DOI
Peter Sykora,
S Kanno,
Mansour Akbari,
T Kulikowicz,
H Lu,
J Tian
et al.:
DNA Polymerase Beta Participates in Mitochondrial DNA Repair
Journal of Molecular Cell Biology 2017
DOI
Mansour Akbari,
Peter Sykora,
Vilhelm A. Bohr
:
Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells
Scientific Reports 2015
DOI
Mansour Akbari,
Maria Morevati,
DL Croteau,
Vilhelm A Bohr
:
The role of DNA base excision repair in brain homeostasis and disease
Mansour Akbari,
Guido Keijzers,
Scott Maynard,
Morten Scheibye-Knudsen,
Claus Desler,
Ian D. Hickson
et al.:
Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair
Kristian Wollen Steen,
Berit Doseth,
Marianne Pedersen Westbye,
Mansour Akbari,
D Kang,
Maria Falkenberg
et al.:
mtSSB may sequester UNG1 at mitochondrial ssDNA and delay uracil processing until the dsDNA conformation is restored
Audun Hanssen-Bauer,
Karin Solvang-Garten,
Karin Margaretha Gilljam,
Kathrin Torseth,
David M. Wilson,
Mansour Akbari
et al.:
The region of XRCC1 which harbours the three most common nonsynonymous polymorphic variants, is essential for the scaffolding function of XRCC1
Mansour Akbari,
Hans Einar Krokan
:
Base excision repair efficiency and mechanism in nuclear extracts are influenced by the ratio between volume of nuclear extraction buffer and nuclei-Implications for comparative studies
Mutation research 2012
DOI
Audun Hanssen-Bauer,
Karin Solvang-Garten,
Mansour Akbari,
Marit Otterlei
:
X-ray repair cross complementing protein 1 in base excision repair
International Journal of Molecular Sciences 2012
ARKIV /
DOI
DL Croteau,
Marie L Rossi,
Chandrika Canugovi,
Jane Tian,
Peter Sykora,
Mahesh Ramamoorthy
et al.:
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity
Audun Hanssen-Bauer,
Karin Solvang-Garten,
Ottar Sundheim,
Javier Pena Diaz,
Sonja Benedikte Andersen,
Geir Slupphaug
et al.:
XRCC1 Coordinates Disparate Responses and Multiprotein Repair Complexes Depending on the Nature and Context of the DNA Damage
Environmental and Molecular Mutagenesis 2011
DOI
Mansour Akbari,
Karin Solvang-Garten,
Audun Hanssen-Bauer,
Nora V. Lieske,
Henrik P Sahlin Pettersen,
Grete Klippenvåg Pettersen
et al.:
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes
Mansour Akbari,
Javier Pena Diaz,
Sonja Benedikte Andersen,
Nina-Beate Liabakk,
Marit Otterlei,
Hans Einar Krokan
:
Extracts of proliferating and non-proliferating human cells display different base excision pathways and repair fidelity
Torkild Visnes,
Berit Doseth,
Henrik Sahlin Pettersen,
Lars Hagen,
Mirta Sousa,
Mansour Akbari
et al.:
Uracil in DNA and its processing by different DNA glycosylases
Philosophical Transactions of the Royal Society of London. Biological Sciences 2009
FULLTEKST /
DOI
Mansour Akbari,
Hans Einar Krokan
:
Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human aging
Mechanisms of Ageing and Development 2008
DOI
Mansour Akbari,
Torkild Visnes,
Hans Einar Krokan,
Marit Otterlei
:
Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis
Marianne Westbye,
Emadoldin Feyzi,
Per Arne Aas,
Cathrine Broberg Vågbø,
Vivi A Talstad,
Bodil Merete Kavli
et al.:
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA
Journal of Biological Chemistry 2008
DOI
Torkild Visnes,
Mansour Akbari,
Lars Hagen,
Geir Slupphaug,
Hans Einar Krokan
:
The rate of base excision repair of uracil is controlled by the initiating glycosylase
Mansour Akbari,
Marit Otterlei,
J Pena-Diaz,
Hans Einar Krokan
:
Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress
Mansour Akbari,
Marit Otterlei,
Javier Pena Diaz,
Hans Einar Krokan
:
Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress
Mansour Akbari,
Marianne Dore Hansen,
Jostein Halgunset,
Frank Skorpen,
Hans Einar Krokan
:
Low copy number DNA template can render polymerase chain reaction error prone in a sequence-dependent manner
Journal of Molecular Diagnostics 2005
Mansour Akbari,
Marit Otterlei,
Javier Pena Diaz,
Per Arne Aas,
Bodil Kavli,
Nina-Beate Liabakk
et al.:
Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells
Nucleic Acids Research (NAR) 2004
Javier Pena Diaz,
Mansour Akbari,
Ottar Sundheim,
ME Farez-Vidal,
S Andersen,
R Sneve
et al.:
Trypanosoma cruzi contains a single detectable uracil-DNA glycosylase and repairs uracil exclusively via short patch base excision repair
Journal of Molecular Biology (JMB) 2004
M Akbari,
C Skjelbred,
I Folling,
Jørn V. Sagen,
HE Krokan
:
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA (Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss
Scandinavian Journal of Clinical and Laboratory Investigation 2004
Mansour Akbari,
C Skjelbred,
I Folling,
J Sagen,
Hans Einar Krokan
:
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA(Leu (UUR))) applied to a Norwegian family with diabetes mellitus and hearing loss
Scandinavian Journal of Clinical and Laboratory Investigation 2004
M Akbari,
C Skjelbred,
Ivar Følling,
J Sagen,
H E Krokan
:
A gel electrophoresis method for detection of mitochondrial DNA mutation (3243 tRNA Leu (UUR)) applied to a Norwegian family with diabetes mellitus and hearing loss
Scandinavian Journal of Clinical and Laboratory Investigation 2004
Per Arne Aas,
Marit Otterlei,
P.Ø Falnes,
Cathrine Vågbø,
Frank Skorpen,
Mansour Akbari
et al.:
Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA
Nature 2003
Bodil Kavli,
Ottar Sundheim,
Mansour Akbari,
Marit Otterlei,
Hilde Nilsen,
Frank Skorpen
et al.:
hUNG2 is the major repair enzyme for removal of uracil from U:A matchers,U:G mismatches and U in single stranded DNA, with SMUG1 as a broad specificity backup
Journal of Biological Chemistry 2002
Katarzyna Maria Psonka-Antonczyk,
Mansour Akbari,
Marit Otterlei,
Hans Einar Krokan,
Bjørn Torger Stokke
:
Uracil-DNA glycosylase (UNG) interacting with mismatched DNA – a single molecule approach
2009
Hans Einar Krokan,
Torkild Visnes,
Berit Doseth,
Mansour Akbari,
Marit Otterlei,
Bodil Merete Kavli
et al.:
Uracil in DNA and its processing
2009
Geir Slupphaug,
Berit Doseth,
Bodil Merete Kavli,
Torkild Visnes,
Lars Hagen,
Kathrin Torseth
et al.:
Genomic uracil processing in mice and men
2009
Geir Slupphaug,
Marianne P. Westbye,
Emadoldin Feyzi,
Per Arne Aas,
Cathrine Broberg Vågbø,
Vivi Talstad
et al.:
Human ABH1 is a predominantly mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA
2008
Hans Einar Krokan,
Bodil Merete Kavli,
Mansour Akbari,
Torkild Visnes,
Henrik P Sahlin Pettersen,
Ottar Sundheim
et al.:
Repair og uracil in DNA by UNG2 and SMUG1 - an update
DNA Repair 2007
Hans Einar Krokan,
Mansour Akbari,
Javier Pena Diaz,
Bodil Merete Kavli,
Marit Otterlei,
Madelene Ericsson
et al.:
Base excision repair proteins in cancer prevention and acquired immune responses
The FEBS Journal 2006
Audun Hanssen-Bauer,
Karin Solvang-Garten,
Mansour Akbari,
Hans Einar Krokan,
Marit Otterlei
:
Functional analysis of XRCC1 associated repair complexes containing the XRCC1 polymorphisms Arg194Trp, Arg280His, and Arg399Gln
2006
Javier Pena Diaz,
Siv Anita Hegre,
Mansour Akbari,
Mirta Sousa,
Ottar Sundheim,
Audun Hanssen-Bauer
et al.:
Recruitment of the chaperone Hsp70 to Base Excision Repair complexes
2005
Marit Otterlei,
Mansour Akbari,
Audun Hanssen-Bauer,
Karin Garten,
David Wilson III,
Sonja Benedikte Andersen
et al.:
Base Excision Repair and Single Strand Break Repair proficient XRCC1 complexes
2005
Mansour Akbari,
Bruno Monterotti,
Hans Einar Krokan,
Marit Otterlei
:
XRCC1-Associated repair complexes (ARC)
2004