Bilde av Heiland, Ines
Photo: Art of moments
Bilde av Heiland, Ines
Árktalaš ja mariinna biologiija instituhtta ines.heiland@uit.no +4777646889 You can find me here

Ines Heiland



  • Anna-Sophia Egger, Eva Rauch, Suraj Sharma, Tobias Kipura, Madlen Hotze, Thomas Mair et al.:
    Linking metabolism and histone acetylation dynamics by integrated metabolic flux analysis of Acetyl-CoA and histone acetylation sites
    Molecular Metabolism 2024 DOI
  • Roland Sauter, Suraj Sharma, Ines Heiland :
    Accounting for NAD Concentrations in Genome-Scale Metabolic Models Captures Important Metabolic Alterations in NAD-Depleted Systems
    Biomolecules 2024 ARKIV / DOI
  • Suraj Sharma, Yin-Chen Hsieh, Jørn Dietze, Mathias Bockwoldt, Øyvind Strømland, Mathias Ziegler et al.:
    Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria
    Metabolites 2022 ARKIV / DOI
  • Jørn Dietze, Alienke van Pijkeren, Anna-Sophia Egger, Mathias Ziegler, Marcel Kwiatkowski, Ines Heiland :
    Natural isotope correction improves analysis of protein modification dynamics
    Analytical and Bioanalytical Chemistry 2021 DOI
  • Mathias Ziegler, Magnus Monnè, Andrey Nikiforov, Gennaro Agrimi, Ines Heiland, Ferdinando Palmieri :
    Welcome to the Family: Identification of the NAD+ Transporter of Animal Mitochondria as Member of the Solute Carrier Family SLC25
    Biomolecules 2021 ARKIV / DOI
  • Verena Panitz, Saša Končarević, Ahmed Sadik, Dennis Friedel, Tobias Bausbacher, Saskia Trump et al.:
    Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma
    Theranostics 2021 ARKIV / DOI
  • Alienke Van Pijkeren, Jørn Dietze, Alejandro Sánchez Brotons, Anna-Sophia Egger, Tim Lijster, Andrei Barcaru et al.:
    Combined metabolic and chemical (CoMetChem) labeling using stable isotopes - A strategy to reveal site-specific histone acetylation and deacetylation rates by LC-MS
    Analytical Chemistry 2021 DOI
  • Soumya R Mohapatra, Ahmed Sadik, Suraj Sharma, Gernot Poschet, Hagen M Gegner, Tobias V Lanz et al.:
    Hypoxia Routes Tryptophan Homeostasis Towards Increased Tryptamine Production
    Frontiers in Immunology 2021 ARKIV / FULLTEKST / DOI
  • Mirja Tamara Prentzell, Ulrike Rehbein, Marti Cadena Sandoval, Ann-Sofie De Meulemeester, Ralf Baumeister, Laura Brohée et al.:
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
    Cell 2021 ARKIV / PROSJEKT / OMTALE / FULLTEKST / DOI
  • Mathias Bockwoldt, Ines Heiland, Karsten Fischer :
    The evolution of the plastid phosphate translocator family
    Planta 2019 DOI
  • Øyvind Strømland, Marc Niere, Andrey Nikiforov, Magali R Van Linden, Ines Heiland, Mathias Ziegler :
    Keeping the balance in NAD metabolism
    Biochemical Society Transactions 2019 ARKIV / DOI
  • Mathias Bockwoldt, Dorothee Houry, Marc Niere, Toni I. Gossmann, Ines Reinartz, Alexander Schug et al.:
    Identification of evolutionary and kinetic drivers of NAD-dependent signaling
    Proceedings of the National Academy of Sciences of the United States of America (PNAS) 24. Jul 2019 ARKIV / DOI
  • Alexander Martin Heberle, Patricia Razquin Navas, Miriam Langelaar-Makkinje, Katharina Kasack, Ahmed Sadik, Erik Faessler et al.:
    The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner
    Life Science Alliance (LSA) 2019 ARKIV / DOI
  • Fabrizio Clarelli, Jingyi Liang, Antal Martinecz, Ines Heiland, Pia Abel zur Wiesch :
    Multi-scale modeling of drug binding kinetics to predict drug efficacy
    Cellular and Molecular Life Sciences (CMLS) 2019 ARKIV / DOI
  • Soumya R. Mohapatra, Ahmed Sadik, Lars-Oliver Tykocinski, Jørn Dietze, Gernot Poschet, Ines Heiland et al.:
    Hypoxia Inducible Factor 1α Inhibits the Expression of Immunosuppressive Tryptophan-2,3-Dioxygenase in Glioblastoma
    Frontiers in Immunology 2019 ARKIV / DOI
  • Arina Afanasyeva, Mathias Bockwoldt, Christopher Cooney, Ines Heiland, Toni Ingolf Gossmann :
    Human long intrinsically disordered protein regions are frequent targets of positive selection
    Genome Research 2018 ARKIV / DOI
  • Isabell Adam, Dyah L. Dewi, Joram Mooiweer, Ahmed Sadik, Soumya R. Mohapatra, Bianca Berdel et al.:
    Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation
    Oncoimmunology 2018 ARKIV / DOI
  • Sascha Schäuble, Anne-Kristin Stavrum, Mathias Bockwoldt, Pål Puntervoll, Ines Heiland :
    SBMLmod: a Python-based web application and web service for efficient data integration and model simulation
    BMC Bioinformatics 2017 FULLTEKST / ARKIV / DOI
  • Dyah L Dewi, Soumya R Mohapatra, Saioa Blanco Cabañes, Isabell Adam, Luis F Somarribas Patterson, Bianca Berdel et al.:
    Suppression of indoleamine-2, 3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer
    Oncoimmunology 2017 DOI
  • Christiane A. Opitz, Ines Heiland :
    Dynamics of NAD-metabolism: everything but constant
    Biochemical Society Transactions 2015 DOI
  • Ines Heiland, K Thedieck :
    Nutrigenomics: Toward a cross-disciplinary understanding of nutrient-driven networks in health and disease: What can we learn from the study of cross-talk in complex protein kinase and metabolic networks?
    Aktuelle Ernãhrungsmedizin 2015 DOI
  • Walter Wencke, Bernd Ketelsen, Gaquerel Emmanuel, Ian T. Baldwin, Kim Sang-Gyu, Ines Heiland :
    Improving the accuracy of expression data analysis in time course experiments using resampling
    BMC Bioinformatics 2014 FULLTEKST / ARKIV / DOI
  • Anne-Kristin Stavrum, Ines Heiland, Stefan Schuster, Pål Puntervoll, Mathias Ziegler :
    Model of tryptophan metabolism, readily scalable using tissue-specific gene expression data
    Journal of Biological Chemistry 2013 ARKIV / DOI
  • Kathrin Schmeisser, Johannes Mannsfeld, Doreen Kuhlow, Sandra Weimer, Steffen Priebe, Ines Heiland et al.:
    Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
    Nature Chemical Biology 2013 DOI
  • Sascha Schäuble, Anne-Kristin Stavrum, Pål Puntervoll, Stefan Schuster, Ines Heiland :
    Effect of substrate competition in kinetic models of metabolic networks
    FEBS Letters 2013 FULLTEKST / DOI
  • Ines Heiland, Christoph Kaleta :
    Stoffwechselanalyse: Neue Wege im Labyrinth entdecken
    Laborwelt 2012
  • Ines Heiland :
    Kinetic regulation of NAD homeostasis
    2022
  • Anze Zupanic, Hans Christopher Bernstein, Ines Heiland :
    Systems biology – Current status and challenges
    Cellular and Molecular Biology 2020 ARKIV / DOI
  • Mathias Bockwoldt, Ines Heiland, Toni Ingolf Gossmann, Thomas Rattei :
    Sequence-Based Analysis of Eukaryotic Protein Evolution
    UiT Norges arktiske universitet 2018
  • Toni Ingolf Gossmann, Arina Afanasyeva, Mathias Bockwoldt, Ines Heiland, Cooney Chris :
    Human intrinsically long disordered protein regions are frequent targets of positive selection
    2017
  • Roland Sauter, Ines Heiland :
    Arctic Marine Bioplastics
    2017
  • Mathias Bockwoldt, Ines Heiland, Gossmann Toni, Mathias Ziegler :
    Phylogenetic and simulation-based analysis of NAD metabolism
    2016
  • Roland Sauter, Ines Heiland :
    Metabolic Modeling of Marine Biomass Conversion
    2016
  • Ines Heiland, Mathias Bockwoldt, Pål Puntervoll, Sascha Schäuble, Anne-Kristin Stavrum :
    Tissue specific models of Trp- and NAD-metabolism — insights into metabolic crosstalk.
    2016
  • Mathias Bockwoldt, Ines Heiland :
    Phylogenetic Analysis of NAD biosynthesis and consumption
    2016
  • Ines Heiland, Mathias Bockwoldt, Anne-Kristin Stavrum, Pål Puntervoll, Mathias Ziegler :
    Tissue specific models of Tryptohan-metabolism — insights into metabolic crosstalk
    2016
  • Mathias Bockwoldt, Anne-Kristin Stavrum, Toni I. Gossmann, Mathias Ziegler, Ines Heiland :
    Dynamics of NAD-metabolism - everything but constant
    2015 OMTALE
  • Carolyn Elliss, Thomas Rattei, Ines Heiland :
    50 Years of FEBS´ Education Training Awards
    FEBS News 2015 FULLTEKST
  • Mathias Bockwoldt, Ines Heiland :
    Phylogenetic Analysis of NAD biosynthesis and consumption
    2015
  • Mathias Bockwoldt, Ines Heiland :
    Use of resampling to improve accuracy of data analysis in time course experiments
    2015
  • Ines Heiland :
    Chemo Informatik: Was hat Tryptophan mit Krebs und Parkinson zu tun?
    Chemie in unserer Zeit 2014 DOI
  • Wencke Walter, Emmanuel Gaquerel, Ian T. Baldwin, Sang-Gyu Kim, Ines Heiland :
    Improving the analysis of high throughput time course data using modelling based approaches
    2014
  • Ines Heiland, Susanne Brandes, Anne-Kristin Stavrum, Christian Bodenstein, Mathias Ziegler :
    NAD-metabolism and the circadian clock -- Unraveling contradictions
    2014
  • Anne-Kristin Stavrum, Ines Heiland, Stefan Schuster, Pål Puntervoll, Mathias Ziegler :
    Predicting pathological metabolic changes using a kinetic model of tryptophan metabolism
    2014
  • Ines Heiland, Susanne Brandes, Anne-Kristin Stavrum, Christian Bodenstein, Mathias Ziegler :
    NAD-metabolism and the circadian clock
    2013
  • Ines Heiland :
    Metabolic modelling: From networks to dynamics and back
    2013

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