2015-2018 Evolution of Seasonal Timers

Collaborators: Andrew Loudon (University of Manchester, UK), Dave Burt (University of Edinburgh, UK),  Takashi Yoshimura (Nagoya University, JP)


2015-2019 Light & Salt: Light & Salt - Thyroid hormone deiodinase paralogues & the evolution of complex life-history strategy in salmonids.

Collaborators: Sam Martin and Dan MacQueen (University of Aberdeen, UK), Lars Ebbesson and Tom Nilsson (University of Bergen, NO), Hugues Dardente (University of Tours, FR), Peter Klaren (Radboud University Nijmegen, NL), Even Jørgensen (University of Tromsø, NO)


2012 – 2014 Epigenetic Light

Collaborators: Valerie Simonneaux (University of Strasbourg, FR)


2009 – 2014    The Physiological and Genomic Basis to the Timing of Life History Transitions in the Atlantic Salmon

Collaborators: Sam Martin (University of Aberdeen, UK)


2008 -  2012 Thyrotrophin signaling at the core of photoperiodic timing

Collaborators: Gerald Lincoln (University of Edinburgh, UK), Bruce Whitelaw (Roslin Institute, UK), Roelof Hut (University of Groningen, NL)


2007 – 2011 Defining the molecular basis of photoperiodism in mammals

Arbeider i CRIStin

  • Strand, Jo Espen Tau; Hazlerigg, David; Jørgensen, Even Hjalmar. Photoperiod revisited: is there a critical day length for triggering a complete parr–smolt transformation in Atlantic salmon Salmo salar?. Journal of Fish Biology 2018; Volum 93. ISSN 0022-1112.s 440 - 480.s doi: 10.1111/jfb.13760.

  • Hazlerigg, David; Lomet, Didier; Lincoln, Gerald A.; Dardente, Hugues. Neuroendocrine correlates of the critical day length response in the Soay sheep. Journal of neuroendocrinology 2018. ISSN 0953-8194.s doi: 10.1111/jne.12631.

  • Lorgan, Marlene; Jørgensen, Even Hjalmar; Jordan, William C.; Martin, Samuel AM; Hazlerigg, David. NFAT5 genes are part of the osmotic regulatory system in Atlantic salmon (Salmo salar). Marine Genomics 2017; Volum 31. ISSN 1874-7787.s 25 - 31.s doi: 10.1016/j.margen.2016.06.004.

  • Saenz de Miera, Cristina; Bothorel, Beatrice; Jaeger, Catherine; Simonneaux, Valerie; Hazlerigg, David. Maternal photoperiod programs hypothalamic thyroid status via the fetal pituitary gland. Proceedings of the National Academy of Sciences of the United States of America 2017; Volum 114 (31). ISSN 0027-8424.s 8408 - 8413.s doi: 10.1073/pnas.1702943114.

  • Hazlerigg, David; Blix, Arnoldus S; Stokkan, Karl-Arne. Waiting for the Sun: The circannual programme of reindeer is delayed by the recurrence of rhythmical melatonin secretion after the arctic night. Journal of Experimental Biology 2017; Volum 220 (21). ISSN 0022-0949.s 3869 - 3872.s doi: 10.1242/jeb.163741.

  • Hau, Michaela; Dominoni, Davide; Casagrande, Stefania; Buck, C. Loren; Wagner, Gabriela; Hazlerigg, David; Greives, Timothy; Hut, Roelof A.. Timing as a sexually selected trait: The right mate at the right moment. Philosophical Transactions of the Royal Society of London. Biological Sciences 2017; Volum 372 (1734). ISSN 0962-8436.s doi: 10.1098/rstb.2016.0249.

  • Lomet, Didier; Cognie, Juliette; Chesneau, Didier; Dubois, Emeric; Hazlerigg, David; Dardente, Hugues. The impact of thyroid hormone in seasonal breeding has a restricted transcriptional signature. Cellular and Molecular Life Sciences (CMLS) 2017; Volum 75 (5). ISSN 1420-682X.s 905 - 919.s doi: 10.1007/s00018-017-2667-x.

  • Tyler, Nicholas J.C.; Gregorini, Pablo; Forchhammer, Mads C.; Stokkan, Karl-Arne; van Oort, Bob; Hazlerigg, David. Behavioral timing without clockwork: Photoperiod-dependent trade-off between predation hazard and energy balance in an Arctic ungulate. Journal of Biological Rhythms 2016; Volum 31 (5). ISSN 0748-7304.s 522 - 533.s doi: 10.1177/0748730416662778.

  • Dardente, Hugues; Wyse, Cathy A.; Lincoln, Gerald A.; Wagner, Gabriela; Hazlerigg, David. Effects of photoperiod extension on clock gene and neuropeptide RNA expression in the SCN of the Soay Sheep. PLoS ONE 2016; Volum 11:e0159201 (7). ISSN 1932-6203.s doi: 10.1371/journal.pone.0159201.

  • Pasquali, Vittorio; Gualtieri, Riccardo; D'Alessandro, Giuseppe; Granberg, Maria Erika; Hazlerigg, David; Cagnetti, Marco; Leccese, Fabio. Monitoring and analyzing of circadian and ultradian locomotor activity based on Raspberry-Pi. Electronics 2016; Volum 5 (3). ISSN 2079-9292.s doi: 10.3390/electronics5030058.

  • Stevenson, Tyler J.; Visser, Marcel E.; Arnold, Walter; Barrett, Perry; Biello, Stephany M.; Dawson, Alistair G.; Denlinger, David L.; Dominoni, Davide M.; Ebling, Francis J.P.; Elton, Sarah; Evans, Neil; Ferguson, Heather M.; Foster, Russell G.; Hau, Michaela; Haydon, Daniel Thomas; Hazlerigg, David; Heideman, Paul D.; Hopcraft, John Grant C.; Jonsson, Nicholas N.; Kronfeld-Schor, Noga; Kumar, Vinod Anil; Lincoln, Gerald A.; Macleod, Ross; Martin, Samuel A.M.; Martinez-Bakker, Michaela E.; Nelson, Randy J.; Reed, Thomas E.; Robinson, Jane E.; Rock, Daniel Joseph E.; Schwartz, William J.; Steffan-Dewenter, Ingolf; Tauber, Eran; Thackeray, Stephen J.; Umstätter, Christina; Yoshimura, Takashi; Helm, Barbara. Disrupted seasonal biology impacts health, food security and ecosystems. Proceedings of the Royal Society of London. Biological Sciences 2015; Volum 282 (1817). ISSN 0962-8452.s doi: 10.1098/rspb.2015.1453.

  • Lorgen, Marlene; Casadei, Elisa; Król, Elżbieta; Douglas, Alex; Birnie, Mike J.; Ebbesson, Lars O.E.; Nilsen, Tom Ole; Jordan, William C.; Jørgensen, Even Hjalmar; Dardente, Hugues; Hazlerigg, David; Martin, Samuel A.M.. Functional divergence of type 2 deiodinase paralogs in the Atlantic salmon. Current Biology 2015; Volum 25 (7). ISSN 0960-9822.s 936 - 941.s doi: 10.1016/j.cub.2015.01.074.

  • Hazlerigg, David. Disrupted clocks make us fat: it ain't necessarily so. Experimental Physiology 2014; Volum 99 (9). ISSN 0958-0670.s 1179 - 1179.s doi: 10.1113/expphysiol.2014.081513.

  • Warren, Ian A.; Ciborowski, Kate L.; Casadei, Elisa; Hazlerigg, David; Martin, Sam; Jordan, William C.; Sumner, Seirian. Extensive local gene duplication and functional divergence among paralogs in Atlantic Salmon. Genome Biology and Evolution 2014; Volum 6 (7). ISSN 1759-6653.s 1790 - 1805.s doi: 10.1093/gbe/evu131.

  • Dardente, Hugues; Hazlerigg, David; Ebling, Francis J.P.. Thyroid hormone and seasonal rhythmicity. Frontiers in Endocrinology 2014; Volum 5:19. ISSN 1664-2392.s doi: 10.3389/fendo.2014.00019.

  • Vilches, Nelson; Spichiger, Carlos; Mendez, Natalia; Abarzua-Catalan, Lorena; Galdames, Hugo; Hazlerigg, David; Richter,, Hans; Torres-Farfan, Claudia. Gestational Chronodisruption Impairs Hippocampal Expression of NMDA Receptor Subunits Grin1b/Grin3a and Spatial Memory in the Adult Offspring. PLoS ONE 2014; Volum 9. ISSN 1932-6203.s doi: 10.1371/journal.pone.0091313.

  • Bae, S-E; Wright, IK; Wyse, C; Samson-Desvignes, N; Le Blanc, P; Laroche, S; Hazlerigg, David; Johnston, JD. Regulation of pituitary MT1 melatonin receptor expression by gonadotrophin-releasing hormone (GnRH) and early growth response factor-1 (Egr-1): In vivo and in vitro studies. PLoS ONE 2014; Volum 9 (3). ISSN 1932-6203.s doi: 10.1371/journal.pone.0090056.

  • Saenz De Miera, C; Monecke, S; Bartzen-Sprauer, J; Laran-Chich, M-P; Pevet, P; Hazlerigg, David; Simonneaux, V. A Circannual Clock Drives Expression of Genes Central for Seasonal Reproduction. Current Biology 2014; Volum 24 (13). ISSN 0960-9822.s 1500 - 1506.s doi: 10.1016/j.cub.2014.05.024.

  • Hazlerigg, David. Analysis of core circadian feedback loop in suprachiasmatic nucleus of mCry1-luc transgenic reporter mouse. Proceedings of the National Academy of Sciences of the United States of America 2013; Volum 110 (23). ISSN 0027-8424.s 9547 - 9552.s doi: 10.1073/pnas.1220894110.

  • Hazlerigg, David. Photoperiodic Variation in CD45-Positive Cells and Cell Proliferation in the Mediobasal Hypothalamus of the Soay Sheep. Chronobiology International 2013; Volum 30 (4). ISSN 0742-0528.s 548 - 558.s doi: 10.3109/07420528.2012.754450.

  • Hazlerigg, David. Circannual Variation in Thyroid Hormone Deiodinases in a Short‐Day Breeder. Journal of neuroendocrinology (Print) 2013; Volum 25 (4). ISSN 0953-8194.s 412 - 421.s doi: 10.1111/jne.12013.

  • Wood, Shona Hiedi; Hazlerigg, David. Forskingsdagene: Dyret Kalendar. Forskingsdagene 2018-09-26 - 2018-09-28 2018.

  • Melum, Vebjørn Jacobsen; Hazlerigg, David; Wood, Shona Hiedi. Dyrenes kalenderstyrte utvikling. 2018.

  • Denker, Elsa; Nilsen, Tom Ole; Tronci, Valentina; Hazlerigg, David; Ebbesson, Lars O.E.. Turning light into hormonal signalling: mapping the melatonin receptive cells in the brain of the juvenile Atlantic salmon (Salmo salar), and circadian and seasonal variations through smoltification. 8th Internaltional Symposium on Fish Endocrinology 2016-06-28 - 2016-07-02 2016.

  • Hazlerigg, David. The Gwinner Lecture (Plenary speech): Evolution of vertebrate seasonal timekeeping. XIV European Biological Rhythms Society Conference 2015-08-02 - 2015-08-06 2015.

  • Hazlerigg, David. Seasonal Synchrony. BioDynamics 2013 2013-09-11 - 2013-09-13 2013.

  • Member of research group