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Bilde av Isaksson, Johan Mattias
Bilde av Isaksson, Johan Mattias
Farmasiija instituhtta johan.isaksson@uit.no +4777644842 41354726 You can find me here

Johan Mattias Isaksson

  • Yannik Karl Heinz Schneider, Anton Liaimer, Johan Mattias Isaksson, Oda Sofie Bye Wilhelmsen, Jeanette Hammer Andersen, Kine Østnes Hansen et al.:
    Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin
    Frontiers in Microbiology 2023 ARKIV / DOI
  • Maxim Brilkov, Martin Jakubec, Victoria Stenbakk, Terje Vasskog, Tone Kristoffersen, Jorunn Pauline Cavanagh et al.:
    Bacterial extracellular vesicles: towards realistic models for bacterial membranes in molecular interaction studies by surface plasmon resonance
    Frontiers in Molecular Biosciences 2023 ARKIV / DOI
  • Philip Ben Rainsford, Fredrik G. Rylandsholm, Martin Jakubec, Mitchell Silk, Eric Juskewitz, Johanna Ulrica Ericson et al.:
    Label-free measurement of antimicrobial peptide interactions with lipid vesicles and nanodiscs using microscale thermophoresis
    Scientific Reports 2023 ARKIV / DOI
  • Philip Ben Rainsford, Birta R. Sarre, Margherita Falavigna, Bjørn Olav Brandsdal, Gøril Eide Flaten, Martin Jakubec et al.:
    WIND-PVPA: Water/Ion NMR Detected PVPA to assess lipid barrier integrity in vitro through quantification of passive water- and ion transport
    Biochimica et Biophysica Acta - Biomembranes 2022 ARKIV / DOI
  • Eric Juskewitz, Ekaterina Mischenko, Vishesh Kumar Dubey, Marte Jenssen, Martin Jakubec, Philip Rainsford et al.:
    Lulworthinone: In Vitro Mode of Action Investigation of an Antibacterial Dimeric Naphthopyrone Isolated from a Marine Fungus
    Marine Drugs 2022 ARKIV / DOI
  • Sara Ullsten-Wahlund, Guillaume Petit, Johan Mattias Isaksson, Ida Kristine Østnes Hansen, Yannik Karl Heinz Schneider, Marte Jenssen et al.:
    Identification of New Purpuroine Analogues from the Arctic Echinodermata Pteraster militaris That Inhibit FLT3-ITD+ AML Cell Lines
    International Journal of Molecular Sciences 2022 ARKIV / DOI
  • Fazlin Pheiffer, Yannik Karl Heinz Schneider, Espen Holst Hansen, Jeanette Hammer Andersen, Johan Mattias Isaksson, Tobias Busche et al.:
    Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp.
    Marine Drugs 2022 ARKIV / DOI
  • Venke Kristoffersen, Marte Jenssen, Heba Raid Jawad, Johan Isaksson, Espen Hansen, Teppo Rämä et al.:
    Two Novel Lyso-Ornithine Lipids Isolated from an Arctic Marine Lacinutrix sp. Bacterium
    Molecules 2021 ARKIV / DOI
  • Marte Jenssen, Venke Kristoffersen, Kumar Motiram-Corral, Johan Isaksson, Teppo Rämä, Jeanette Hammer Andersen et al.:
    Chlovalicin B, a Chlorinated Sesquiterpene Isolated from the Marine Mushroom Digitatispora marina
    Molecules 2021 ARKIV / DOI
  • Marte Jenssen, Philip Rainsford, Eric Juskewitz, Jeanette Hammer Andersen, Espen Hansen, Johan Isaksson et al.:
    Lulworthinone, a New Dimeric Naphthopyrone From a Marine Fungus in the Family Lulworthiaceae With Antibacterial Activity Against Clinical Methicillin-Resistant Staphylococcus aureus Isolates
    Frontiers in Microbiology 2021 ARKIV / DOI
  • Marianne Hagensen Paulsen, Magnus Engqvist, Dominik Ausbacher, Trude Anderssen, Manuel K- Langer, Tor Haug et al.:
    Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates
    Journal of Medicinal Chemistry 2021 ARKIV / DOI
  • Ikenna E. Ndukwe, Yu-hong Lam, Sunil Kumar Pandey, Bengt Erik Haug, Annette Bayer, Edward C. Sherer et al.:
    Unequivocal structure confirmation of a breitfussin analog by anisotropic NMR measurements
    Chemical Science 21. Sep 2020 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Marte Jenssen, Johan Isaksson, Kine Østnes Hansen, Jeanette Hammer Andersen, Espen Hansen :
    Bioactivity of Serratiochelin A, a Siderophore Isolated from a Co-Culture of Serratia sp. and Shewanella sp.
    Microorganisms 14. Jul 2020 ARKIV / DOI
  • Worku Dinku, Johan Isaksson, Fredrik G. Rylandsholm, Petr Bouř, Eva Brichtova, Sang Un Choi et al.:
    Anti-proliferative activity of a novel tricyclic triterpenoid acid from Commiphora africana resin against four human cancer cell lines
    Applied Biological Chemistry 2020 ARKIV / DOI
  • Yngve Guttormsen, Magnus John Espeland Fairhurst, Sunil Kumar Pandey, Johan Isaksson, Bengt Erik Haug, Annette Bayer :
    Total synthesis of phorbazole B
    Molecules 21. Oct 2020 ARKIV / PROSJEKT / DOI
  • Olena Dobrovolska, Maxim Brilkov, Noëlly Madeleine, Øyvind Ødegaard-Fougner, Øyvind Strømland, Stephen R. Martin et al.:
    The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection
    The FEBS Journal 2020 ARKIV / DOI
  • Ida Kristine Østnes Hansen, Johan Isaksson, Aaron G. Poth, Kine Østnes Hansen, Aaron John Christian Andersen, Céline Sarah Marine Richard et al.:
    Isolation and characterization of antimicrobial peptides with unusual disulfide connectivity from the colonial ascidian Synoicum turgens
    Marine Drugs 2020 ARKIV / DOI
  • Yannik Karl-Heinz Schneider, Kine Østnes Hansen, Johan Isaksson, Sara Maria Ullsten-Wahlund, Espen Hansen, Jeanette Hammer Andersen :
    Anti-Bacterial Effect and Cytotoxicity Assessment of Lipid 430 Isolated from Algibacter sp.
    Molecules 2019 ARKIV / DOI
  • Kine Østnes Hansen, Jeanette hammer Andersen, Annette Bayer, Sunil Kumar Pandey, Marianne Lorentzen, Kåre Bredeli Jørgensen et al.:
    Kinase chemodiversity from the Arctic: the breitfussins
    Journal of Medicinal Chemistry 2019 ARKIV / DOI
  • Aitor Moreno, Kine Østnes Hansen, Johan Isaksson :
    CSSF-CLIP-HSQMBC: measurement of heteronuclear coupling constants in severely crowded spectral regions
    RSC Advances 2019 ARKIV / DOI
  • Raja Priyanka Mary Michael Siranjeevi, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a new alkaloid from the Arctic marine bryozoan Dendrobeania murrayana
    Natural Product Research 2019 ARKIV / DOI
  • Sundus Ahkter, Bjarte Aarmo Lund, Aya Ismael, Manuel Langer, Johan Isaksson, Tony Christopeit et al.:
    A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design
    European Journal of Medicinal Chemistry 2018 ARKIV / DOI
  • Kine Østnes Hanssen, Johan Isaksson, Eirin Glomsaker, Jeanette hammer Andersen, Espen Hansen :
    Ponasterone A and F, Ecdysteroids from the Arctic Bryozoan Alcyonidium gelatinosum
    Molecules 2018 ARKIV / DOI
  • Jostein Grip, Rolf Einar Engstad, Ingrid Skjæveland, Natasa Skalko-Basnet, Johan Isaksson, Purusotam Basnet et al.:
    Beta-glucan-loaded nanofiber dressing improves wound healing in diabetic mice
    European Journal of Pharmaceutical Sciences 2018 ARKIV / DOI
  • Bjarte Aarmo Lund, Ane Molden Thomassen, Birgit Helene Berg Nesheim, Trine Josefine Olsen Carlsen, Johan Isaksson, Tony Christopeit et al.:
    The biological assembly of OXA‐48 reveals a dimer interface with high charge complementarity and very high affinity
    The FEBS Journal 2018 DOI
  • Venke Kristoffersen, Teppo Rämä, Johan Isaksson, Jeanette hammer Andersen, William H. Gerwick, Espen Hansen :
    Characterization of Rhamnolipids Produced by an Arctic Marine Bacterium from the Pseudomonas fluorescence Group
    Marine Drugs 2018 ARKIV / DOI
  • Raja Priyanka Mary Michael Siranjeevi, Kine Østnes Hanssen, Johan Isaksson, Jeanette hammer Andersen, Espen Hansen :
    A Novel Brominated Alkaloid Securidine A, Isolated from the Marine Bryozoan Securiflustra securifrons
    Molecules 2017 ARKIV / DOI
  • Kine Østnes Hansen, Johan Isaksson, Annette Bayer, Jostein a Johansen, Jeanette hammer Andersen, Espen Hansen :
    Securamine Derivatives from the Arctic Bryozoan Securiflustra securifrons
    Journal of natural products 2017 DOI
  • Ulli Rothweiler, Wenche Stensen, Bjørn Olav Brandsdal, Johan Isaksson, Frederick Alan Leeson, Richard Alan Engh et al.:
    Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules
    Journal of Medicinal Chemistry 2016 DOI
  • Elisabeth Klungerbo Olsen, Espen Hansen, Lindon W.K Moodie, Johan Isaksson, Kristina Sepcic, Marija Cergolj et al.:
    Marine AChE inhibitors isolated from Geodia barretti: natural compounds and their synthetic analogs
    Organic and biomolecular chemistry 2016 DOI
  • Elisabeth Klungerbo Olsen, Kine Søderholm, Johan Isaksson, Jeanette hammer Andersen, Espen Hansen :
    Metabolomic Profiling Reveals the N-Acyl-Taurine Geodiataurine in Extracts from the Marine Sponge Geodia macandrewii (Bowerbank)
    Journal of natural products 2016 DOI
  • Yannik Karl Heinz Schneider, Anton Liaimer, Johan Mattias Isaksson, Oda Sofie Bye Wilhelmsen, Jeanette Hammer Andersen, Kine Østnes Hansen et al.:
    Corrigendum: Four new suomilides isolated from the cyanobacterium Nostoc sp. KVJ20 and proposal of their biosynthetic origin (Frontiers in Microbiology, (2023), 14, (1130018), 10.3389/fmicb.2023.1130018)
    Frontiers in Microbiology 2023 DOI
  • Maxim Brilkov, Jorunn Pauline Cavanagh, Johan Mattias Isaksson, Johanna E. Sollid, Gøril Eide Flaten :
    BACTERIALLY PRODUCED IN VITRO MEMBRANE MODEL SYSTEMS FROM RESISTANT- AND NON-RESISTANT CLINICAL ISOLATES
    2023
  • Maxim Brilkov, Jorunn Pauline Cavanagh, Johan Mattias Isaksson, Johanna U Ericson :
    Outer-membrane vesicles as a bacterial membrane model to study interaction of antimicrobial peptides
    2023
  • Philip Ben Rainsford, Maxim Brilkov, Finn Lillelund Aachmann, Gøril Eide Flaten, Johan Mattias Isaksson :
    NMR tube inserts for time-resolved spatial NMR
    2023
  • Monika Krupova, Karolina Di Remigio Eikås, Johan Mattias Isaksson, Kenneth Ruud :
    Vibrational Circular Dichroism of Antimicrobial Peptides: What is Their Structure in Solution and in Membranes?
    2022
  • Philip Ben Rainsford, Johan Mattias Isaksson :
    Expanding the toolbox for the study of antimicrobial peptides
    UiT Norges arktiske universitet 2022
  • Maxim Bril'kov, Jorunn Pauline Cavanagh, Johan Mattias Isaksson, Johanna U Ericson, Gøril Eide Flaten :
    Bacterially produced in vitro mambrane model systems from resistant- and non-resistant clinical isolates
    2022
  • Johan Isaksson :
    CSSF-CLIP-HSQMBC: Measurement of heteronuclear coupling constants in severely crowded spectral regions
    2020
  • Kine Ø. Hanssen, Jeanette hammer Andersen, Bert Klebl, Jan Eickhoff, Johan Isaksson, Espen Hansen :
    Novel kinase inhibitors from the Arctic marine hydrozoan Thuiaria breitfussi
    2019
  • Priyanka Michael, Espen Hansen, Johan Isaksson, Jeanette hammer Andersen, Kine Østnes Hansen :
    Dendrobeaniamine A, a New Alkaloid from the Arctic Marine bryozoan Dendrobeania murrayana
    2019
  • Aitor Moreno, Kine Ø. Hanssen, Johan Isaksson :
    CSSF-CLIP-HSQMBC: Measurement of heteronuclear coupling constants in severely crowded spectral regions
    2019
  • Johan Isaksson :
    CSSF-CLIP-HSQMBC: Measurement of heteronuclear coupling constants in severely crowded spectral regions
    2019
  • Johan Isaksson, Birta Ravdna Sarre :
    “Dynamics characterization of dUTPase, a new target in cancer therapy”
    2018
  • Marc Boomgaren, Birta Ravdna Sarre, Tor Arne Heim Andberg, Bjørn Olav Brandsdal, Johan Isaksson, Jørn H Hansen :
    Synthesis and exploration of a novel molecular scaffold for dUTPase inhibition: Aiming for new anticancer agents
    2017
  • Tor Haug, Runar Gjerp Solstad, Chun Li, Johan Isaksson, Jostein a Johansen, Johan Svenson et al.:
    Halogenated antimicrobial peptides from the red sea urchin, Echinus esculentus.
    2017
  • Elisabeth Klungerbo Olsen, Kine Søderholm, Johan Isaksson, Jeanette hammer Andersen, Espen Hansen :
    Metabolomic Profiling of Two Related Marine Sponges From the Coast of Norway Reveals a New N-acyl Taurine
    2016
  • Elisabeth Klungerbo Olsen, Espen Hansen, Lindon W.K Moodie, Johan Isaksson, Kristina Sepcic, Marija Cergolj et al.:
    ChemInform Abstract: Marine AChE Inhibitors Isolated from Geodia barretti: Natural Compounds and Their Synthetic Analogues
    ChemInform 2016 DOI
  • Bjarte Aarmo Lund, Tony Christopeit, Sundus Ahkter, Yngve Guttormsen, Johan Isaksson, Annette Bayer et al.:
    Structure-Guided Drug Design for the Antibiotic Resistance Enzyme OXA-48
    2016
  • Runar Gjerp Solstad, Chun Li, Johan Isaksson, Jostein a Johansen, Johan Svenson, Klara Stensvåg et al.:
    Novel antimicrobial peptides EeCentrocins 1, 2 and EeStrongylocin 2 from the edible sea urchin Echinus esculentus have 6-Br-Trp post-translational modifications
    2016

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